Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10048221 | 0.91 | P2RX3 (0.79) | P2RX3 | |
| SCHEMBL10048377 | 0.86 | P2RX3 (1.00) | P2RX3 | |
| SCHEMBL10048202 | 0.85 | P2RX3 (1.00) | P2RX3 | |
| SCHEMBL10048218 | 0.85 | P2RX3 (0.79) | P2RX3 | |
| SCHEMBL15215756 | 0.80 | P2RX3 (1.00) | P2RX3 | |
| SCHEMBL15215759 | 0.79 | P2RX3 (1.00) | P2RX3 | |
| SCHEMBL12060340 | 0.78 | P2RX3 (1.00) | P2RX3 | |
| SCHEMBL10048219 | 0.76 | P2RX3 (1.00) | P2RX3 | |
| SCHEMBL15038621 | 0.76 | P2RX3 (0.81) | P2RX3 | |
| SCHEMBL9983230 | 0.74 | P2RX3 (1.00) | P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604260-B1 | NOVEL HETEROCYCLIC DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | SHIONOGI & CO (JP) | 2017-05-10 | — | — | EP | disclosed |