Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 10/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | MTAP | Q13126 | 8/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16883367 | 1.00 | PNP (0.38) | PNPDYRK1AMTAP | |
| SCHEMBL18556481 | 1.00 | PNP (0.38) | PNPDYRK1AMTAP | |
| SCHEMBL16883370 | 0.78 | PNP (0.34) | PNP | |
| SCHEMBL18840641 | 0.74 | PNP (0.36) | PNPDYRK1AMTAP | |
| SCHEMBL16883369 | 0.74 | PNP (0.41) | PNPMTAP | |
| SCHEMBL18840646 | 0.74 | PNP (0.36) | PNPDYRK1AMTAP | |
| SCHEMBL15612909 | 0.74 | PNP (0.40) | PNPDYRK1AMTAP | |
| SCHEMBL15613116 | 0.74 | PNP (0.40) | PNPDYRK1AMTAP | |
| SCHEMBL16883383 | 0.69 | PNP (0.32) | PNP | |
| SCHEMBL16883384 | 0.69 | PNP (0.32) | PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170128454-A1 | COMPOSITIONS AND METHODS FOR INHIBITING VIRAL POLYMERASE | BIOCRYST PHARMACEUTICALS, INC. | 2017-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170128454-A1 | COMPOSITIONS AND METHODS FOR INHIBITING VIRAL POLYMERASE | POLRMT, POLR1E, POLR1A | PNP 71/4885DYRK1A 4874/4885MTAP 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.