SCHEMBL1884075

SCHEMBL1884075

CCN(C(=O)[C@@H]1C=C2c3cccc4[nH]cc(c34)C[C@H]2N(C)C1)C(C)Br

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTR2A P28223 11/20 0.77
▸ HTR2C P28335 2/20 0.77
▸ ADRB2 P07550 1/20 0.77
▸ ADRB1 P08588 1/20 0.77
▸ HTR1A P08908 1/20 0.77
▸ DRD2 P14416 1/20 0.77
▸ DRD4 P21917 1/20 0.77
▸ DRD5 P21918 1/20 0.77
▸ HTR1D P28221 1/20 0.77
▸ HTR1E P28566 1/20 0.77
▸ HTR7 P34969 1/20 0.77
▸ HRH1 P35367 1/20 0.77
▸ DRD3 P35462 1/20 0.77
▸ HTR2B P41595 1/20 0.77
▸ HTR5A P47898 1/20 0.77
▸ HTR6 P50406 1/20 0.77
▸ KDM4E B2RXH2 1/20 0.65
▸ MEN1 O00255 1/20 0.65
▸ USP2 O75604 1/20 0.65
▸ MAPT P10636 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1889935 0.99 HTR2A (0.76) HTR2AHTR2CADRB2ADRB1HTR1A
SCHEMBL30886892 0.93 HTR2A (0.80) HTR2AHTR2CADRB2ADRB1HTR1A
SCHEMBL20970933 0.93 HTR2A (0.80) HTR2AHTR2CADRB2ADRB1HTR1A
SCHEMBL30886886 0.93 HTR2A (0.80) HTR2AHTR2CADRB2ADRB1HTR1A
Lysergide SCHEMBL28318015 0.88 HTR2A (0.94) HTR2AHTR2CADRB2ADRB1HTR1A
Lysergide SCHEMBL28097238 0.88 HTR2A (0.94) HTR2AHTR2CADRB2ADRB1HTR1A
Lysergide SCHEMBL23741954 0.87 HTR2A (1.00) HTR2AHTR2CADRB2ADRB1HTR1A
Lysergide SCHEMBL113755 0.87 HTR2A (1.00) HTR2AHTR2CADRB2ADRB1HTR1A
Lysergide SCHEMBL12401704 0.87 HTR2A (1.00) HTR2AHTR2CADRB2ADRB1HTR1A
Lysergide SCHEMBL467940 0.87 HTR2A (1.00) HTR2AHTR2CADRB2ADRB1HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250129064-A1 PRODRUGS OF 2-BROMO-LSD (2-BROMOLYSERGIC ACID DIETHYLAMIDE) TERRAN BIOSCIENCES INC. 2025-04-24 — — US disclosed
WO-2025080689-A1 LIPID PRODRUGS OF BROMOLYSERGIDE AND USES THEREOF SEAPORT THERAPEUTICS, INC. (US) 2025-04-17 — — WO disclosed
WO-2025080689-A1 LIPID PRODRUGS OF BROMOLYSERGIDE AND USES THEREOF SEAPORT THERAPEUTICS, INC. (US) 2025-04-17 — — WO disclosed
WO-2023141636-A1 PRODRUGS OF 2-BROMO-LSD (2-BROMOLYSERGIC ACID DIETHYLAMIDE) TERRAN BIOSCIENCES INC. (US) 2023-07-27 — — WO disclosed
WO-2023107966-A1 SALT AND SOLID FORMS OF LYSERGIC ACID DIETHYLAMIDE (LSD) AND ANALOGS TERRAN BIOSCIENCES, INC. (US) 2023-06-15 — — WO disclosed
CN-102164603-B Be used for the treatment of method and the test kit of cluster headache disease THE MCLEAN HOSPITAL CORP. (US) 2015-11-25 — — CN disclosed
CN-102164603-B Be used for the treatment of method and the test kit of cluster headache disease THE MCLEAN HOSPITAL CORP. (US) 2015-11-25 — — CN disclosed
US-20130252996-A1 METHODS AND KITS FOR TREATING CLUSTER HEADACHE DISORDERS MEDIZINISCHE HOCHSCHULE HANNOVER (DE) 2013-09-26 — — US disclosed
US-20130252996-A1 METHODS AND KITS FOR TREATING CLUSTER HEADACHE DISORDERS MEDIZINISCHE HOCHSCHULE HANNOVER (DE) 2013-09-26 — — US disclosed
US-8415371-B2 Methods and kits for treating cluster headache disorders THE MCLEAN HOSPITAL CORPORATION (US) 2013-04-09 — — US disclosed
CN-102657868-A 5-hydroxy tryptamine 2 receptor antagonist or transporter inhibitor for treating fatty liver or hyperlipemia UNIV CHINA PHARMA 2012-09-12 — — CN disclosed
CN-102164603-A Methods and kits for treating cluster headache disorders MCLEAN HOSPITAL CORP 2011-08-24 — — CN disclosed
CN-102164603-A Methods and kits for treating cluster headache disorders MCLEAN HOSPITAL CORP 2011-08-24 — — CN disclosed
EP-2331100-A2 METHODS AND KITS FOR TREATING CLUSTER HEADACHE DISORDERS The McLean Hospital Corporation (US) 2011-06-15 — — EP disclosed
EP-2331100-A2 METHODS AND KITS FOR TREATING CLUSTER HEADACHE DISORDERS The McLean Hospital Corporation (US) 2011-06-15 — — EP disclosed
US-20110104275-A1 METHODS AND KITS FOR TREATING CLUSTER HEADACHE DISORDERS THE MCLEAN HOSPITAL CORPORATION (US) 2011-05-05 — — US disclosed
US-20110104275-A1 METHODS AND KITS FOR TREATING CLUSTER HEADACHE DISORDERS THE MCLEAN HOSPITAL CORPORATION (US) 2011-05-05 — — US disclosed
WO-2010033392-A3 METHODS AND KITS FOR TREATING CLUSTER HEADACHE DISORDERS THE MCLEAN HOSPITAL CORPORATION (US) 2010-06-17 — — WO disclosed
WO-2010033392-A2 METHODS AND KITS FOR TREATING CLUSTER HEADACHE DISORDERS THE MCLEAN HOSPITAL CORPORATION (US) 2010-03-25 — — WO disclosed
WO-2010033392-A2 METHODS AND KITS FOR TREATING CLUSTER HEADACHE DISORDERS THE MCLEAN HOSPITAL CORPORATION (US) 2010-03-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110104275-A1 METHODS AND KITS FOR TREATING CLUSTER HEADACHE DISORDERS KIT, CCKBR, HCRTR2 HTR2A 46/4885HTR2C 73/4885ADRB2 482/4885
US-20130252996-A1 METHODS AND KITS FOR TREATING CLUSTER HEADACHE DISORDERS KIT, CCKBR, HCRTR2 HTR2A 46/4885HTR2C 73/4885ADRB2 482/4885
US-20250129064-A1 PRODRUGS OF 2-BROMO-LSD (2-BROMOLYSERGIC ACID DIETHYLAMIDE) GBA2, GBA1, SLC18A2 HTR2A 9/4885HTR2C 16/4885ADRB2 308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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