Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.64 |
| ▸ | TGM2 | P21980 | 1/20 | 0.59 |
| ▸ | HINT1 | P49773 | 1/20 | 0.56 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.55 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.55 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.55 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.55 |
| ▸ | KRAS | P01116 | 4/20 | 0.53 |
| ▸ | IMPDH2 | P12268 | 5/20 | 0.53 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.53 |
| ▸ | GSK3A | P49840 | 2/20 | 0.53 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8897427 | 0.86 | NT5E (0.65) | NT5ETGM2HINT1FUT5KRAS | |
| SCHEMBL1299520 | 0.85 | NT5E (0.58) | NT5ETGM2HINT1STING1PDE3B | |
| SCHEMBL1299533 | 0.85 | NT5E (0.58) | NT5ETGM2HINT1STING1PDE3B | |
| SCHEMBL94114 | 0.83 | NT5E (0.64) | NT5ETGM2HINT1FUT5KRAS | |
| SCHEMBL1971280 | 0.83 | NT5E (0.64) | NT5ETGM2HINT1FUT5KRAS | |
| SCHEMBL1533806 | 0.83 | NT5E (0.64) | NT5ETGM2HINT1FUT5KRAS | |
| SCHEMBL1971274 | 0.83 | NT5E (0.64) | NT5ETGM2HINT1FUT5KRAS | |
| Phosphoric Acid SCHEMBL25402859 | 0.83 | NT5E (0.63) | NT5ETGM2HINT1STING1PDE3B | |
| Phosphoric Acid SCHEMBL1299515 | 0.83 | NT5E (0.63) | NT5ETGM2HINT1STING1PDE3B | |
| E626 SCHEMBL21803790 | 0.83 | NT5E (0.83) | NT5ETGM2HINT1PDE3AFUT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9790531-B2 | Enzymes and polymerases for the synthesis of RNA | MODERNATX, INC. (US) | 2017-10-17 | — | — | US | disclosed |
| US-20170130255-A1 | ENZYMES AND POLYMERASES FOR THE SYNTHESIS OF RNA | MODERNATX, INC. (US) | 2017-05-11 | — | — | US | disclosed |