⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL288886 | 0.96 | — | — | |
| SCHEMBL6012129 | 0.87 | — | — | |
| SCHEMBL19841888 | 0.85 | CXCR4 (0.42) | — | |
| SCHEMBL19889810 | 0.85 | ALDH1A1 (0.42) | — | |
| Hydrochloric Acid SCHEMBL939538 | 0.85 | CXCR4 (0.35) | — | |
| SCHEMBL7745275 | 0.83 | ALDH1A1 (0.47) | — | |
| SCHEMBL2695126 | 0.81 | CYP2D6 (0.34) | — | |
| SCHEMBL21305079 | 0.81 | HIF1A (0.35) | — | |
| SCHEMBL28016430 | 0.81 | TSHR (0.33) | — | |
| SCHEMBL18898243 | 0.79 | CXCR4 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219954-A1 | P2X3 AND/OR P2X2/3 COMPOUNDS AND METHODS | ASANA BIOSCIENCES, LLC | 2023-07-13 | — | — | US | claimed |
| US-11685736-B2 | P2X3 and/or P2X2/3 compounds and methods | ABS DEVELOPMENT 1, INC. (US) | 2023-06-27 | — | — | US | claimed |
| WO-2022011274-A1 | SUBSTITUTED 1,6-NAPHTHYRIDINE INHIBITORS OF CDK5 | GOLDFINCH BIO, INC. (US) | 2022-01-13 | — | — | WO | claimed |
| EP-3083619-B1 | P2X3 AND/OR P2X2/3 COMPOUNDS AND METHODS | ASANA BIOSCIENCES LLC (US) | 2021-11-03 | — | — | EP | claimed |
| CN-113288938-A | Antiviral traditional Chinese medicine composition | 安徽鑫全康药业有限公司 | 2021-08-24 | — | — | CN | claimed |
| EP-3793976-A1 | INDOLE COMPOUNDS, PROCESS FOR THE PREPARATION AND USE THEREOF | Council of Scientific & Industrial Research (IN) | 2021-03-24 | — | — | EP | claimed |
| US-20200109143-A1 | P2X3 AND/OR P2X2/3 COMPOUNDS AND METHODS | ABS DEVELOPMENT 1, INC. | 2020-04-09 | — | — | US | claimed |
| US-10590127-B2 | P2X3 and/or P2X2/3 compounds and methods | ASANA BIOSCIENCES, LLC (US) | 2020-03-17 | — | — | US | claimed |
| US-10544145-B2 | P2X3 and/or P2X2/3 compounds and methods | ASANA BIOSCIENCES, LLC (US) | 2020-01-28 | — | — | US | claimed |
| CN-106029660-B | P2X3And/or P2X2/3Compounds and methods | 阿萨纳生物科技有限责任公司 | 2019-11-15 | — | — | CN | claimed |
| US-5716953-A | MODIFIERS OF GASTRIN AND CHOLECYSTOKININS | GLAXO WELLCOME S.P.A. (IT) | 1998-02-10 | — | — | US | claimed |
| WO-1997036587-A1 | A METHOD OF TREATING CANCER | MERCK & CO., INC. (US) | 1997-10-09 | — | — | WO | claimed |
| EP-0507672-B1 | N-cyclohexyl benzamides derivatives, preparations and therapeutic applications thereof | LOGEAIS LABOR JACQUES (FR) | 1997-06-04 | — | — | EP | claimed |
| US-5585376-A | 1,5-benzodiazepine derivatives having CCK and/or gastrin antagonistic activity | GLAXO WELLCOME INC. (US) | 1996-12-17 | — | — | US | claimed |
| EP-0694040-A1 | 1,5 BENZODIAZEPINE DERIVATIVES HAVING CCK AND/OR GASTRIN ANTAGONISTIC ACTIVITY | GLAXO WELLCOME INC. (US) | 1996-01-31 | — | — | EP | claimed |
| WO-1994024151-A1 | 1,5 BENZODIAZEPINE DERIVATIVES HAVING CCK AND/OR GASTRIN ANTAGONISTIC ACTIVITY | GLAXO INC. (US) | 1994-10-27 | — | — | WO | claimed |
| EP-0290145-B1 | Aliphatic carboxamides | ICI AMERICA INC (US) | 1994-10-26 | — | — | EP | claimed |
| US-5273983-A | 2-Piperidinylmethylcyclohexylaminocarbonyl-substituted benzene | LABORATORIES JACQUES LOGEAIS (FR) | 1993-12-28 | — | — | US | claimed |
| EP-0507672-A1 | N-cyclohexyl benzamides derivatives, preparations and therapeutic applications thereof | LABORATOIRES JACQUES LOGEAIS Société dite: (FR) | 1992-10-07 | — | — | EP | claimed |
| EP-0290145-A1 | Aliphatic carboxamides | ZENECA INC. (US) | 1988-11-09 | — | — | EP | claimed |