Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.68 |
| ▸ | TP53 | P04637 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | RARA | P10276 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | MTOR | P42345 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL2944670 | 1.00 | RARB (0.68) | RARBTP53TSHRPLA2G4BALDH1A1 | |
| Terephthalic Acid SCHEMBL28502502 | 0.97 | TP53 (0.71) | RARBTP53TSHRPLA2G4BALDH1A1 | |
| Terephthalic Acid SCHEMBL28142960 | 0.97 | TP53 (0.71) | RARBTP53TSHRPLA2G4BALDH1A1 | |
| Tetradecane SCHEMBL30605685 | 0.97 | TP53 (0.71) | RARBTP53TSHRPLA2G4BALDH1A1 | |
| Dodecane SCHEMBL9354416 | 0.97 | TP53 (0.71) | RARBTP53TSHRPLA2G4BALDH1A1 | |
| Terephthalic Acid SCHEMBL28103847 | 0.97 | RARB (0.66) | RARBTP53TSHRPLA2G4BALDH1A1 | |
| Terephthalic Acid SCHEMBL25418895 | 0.95 | RARB (0.63) | RARBTP53TSHRPLA2G4BALDH1A1 | |
| Terephthalic Acid SCHEMBL27433040 | 0.95 | RARB (0.64) | RARBTP53TSHRPLA2G4BALDH1A1 | |
| Terephthalic Acid SCHEMBL28812818 | 0.93 | RARB (0.61) | RARBTP53TSHRPLA2G4BALDH1A1 | |
| Paraben SCHEMBL9770340 | 0.91 | CA12 (0.70) | RARBTP53TSHRPLA2G4BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7939819-B2 | Circuit board, electro-optical device, and electric apparatus | SEIKO EPSON CORPORATION (JP) | 2011-05-10 | — | — | US | disclosed |
| US-20070215377-A1 | CIRCUIT BOARD, ELECTRO-OPTICAL DEVICE, AND ELECTRIC APPARATUS | SEIKO EPSON CORPORATION (JP) | 2007-09-20 | — | — | US | disclosed |