Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.68 |
| ▸ | TP53 | P04637 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | PLA2G4B | P0C869 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | RARA | P10276 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | MTOR | P42345 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL1884274 | 1.00 | RARB (0.68) | RARBTP53TSHRPLA2G4BALDH1A1 | |
| Terephthalic Acid SCHEMBL28502502 | 0.97 | TP53 (0.71) | RARBTP53TSHRPLA2G4BALDH1A1 | |
| Terephthalic Acid SCHEMBL28142960 | 0.97 | TP53 (0.71) | RARBTP53TSHRPLA2G4BALDH1A1 | |
| Tetradecane SCHEMBL30605685 | 0.97 | TP53 (0.71) | RARBTP53TSHRPLA2G4BALDH1A1 | |
| Dodecane SCHEMBL9354416 | 0.97 | TP53 (0.71) | RARBTP53TSHRPLA2G4BALDH1A1 | |
| Terephthalic Acid SCHEMBL28103847 | 0.97 | RARB (0.66) | RARBTP53TSHRPLA2G4BALDH1A1 | |
| Terephthalic Acid SCHEMBL25418895 | 0.95 | RARB (0.63) | RARBTP53TSHRPLA2G4BALDH1A1 | |
| Terephthalic Acid SCHEMBL27433040 | 0.95 | RARB (0.64) | RARBTP53TSHRPLA2G4BALDH1A1 | |
| Terephthalic Acid SCHEMBL28812818 | 0.93 | RARB (0.61) | RARBTP53TSHRPLA2G4BALDH1A1 | |
| Paraben SCHEMBL9770340 | 0.91 | CA12 (0.70) | RARBTP53TSHRPLA2G4BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543975-A1 | STABILISER COMPOSITION, USE OF THE STABILISER COMPOSITION, METHOD FOR STABILISING CONDENSATION POLYMERS AGAINST HYDROLYTIC DEGRADATION, AND HYDROLYSIS-STABILISED COMPOSITION AND MOULDING OR MOULDED PART CONSISTING THEREOF | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2025-04-30 | — | — | EP | claimed |
| WO-2024002610-A1 | STABILISER COMPOSITION, USE OF THE STABILISER COMPOSITION, METHOD FOR STABILISING CONDENSATION POLYMERS AGAINST HYDROLYTIC DEGRADATION, AND HYDROLYSIS-STABILISED COMPOSITION AND MOULDING OR MOULDED PART CONSISTING THEREOF | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2024-01-04 | — | — | WO | claimed |
| EP-2094786-A1 | FLAMEPROOF THERMOPLASTIC RESIN COMPOSITION | Cheil Industries Inc. (KR) | 2009-09-02 | — | — | EP | claimed |
| WO-2008062924-A1 | FLAMEPROOF THERMOPLASTIC RESIN COMPOSITION | CHEIL INDUSTRIES INC. (KR) | 2008-05-29 | — | — | WO | claimed |
| US-20250326927-A1 | CRYSTALLIZABLE RESINS | ALIGN TECHNOLOGY INC (US) | 2025-10-23 | — | — | US | disclosed |
| US-20250136867-A1 | POLYMERIZABLE COMPOUNDS FOR ORTHODONTIC DEVICES | ALIGN TECHNOLOGY, INC. | 2025-05-01 | — | — | US | disclosed |
| US-12215223-B2 | Crystallizable resins | ALIGN TECHNOLOGY, INC. (US) | 2025-02-04 | — | — | US | disclosed |
| EP-4041119-A2 | CRYSTALLIZABLE RESINS | Align Technology, Inc. (US) | 2022-08-17 | — | — | EP | disclosed |
| CN-114727856-A | Crystallizable resin | 阿莱恩技术有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-105324439-B | resin composition for molding | 三井化学株式会社 | 2017-09-01 | — | — | CN | disclosed |
| US-20160160044-A1 | MOLDING RESIN COMPOSITION | MITSUI CHEMICALS. INC. (JP) | 2016-06-09 | — | — | US | disclosed |
| EP-3015510-A1 | MOLDING RESIN COMPOSITION | Mitsui Chemicals, Inc. (JP) | 2016-05-04 | — | — | EP | disclosed |
| CN-104220258-A | Polyester film, method for producing same, back sheet for solar cell, and solar cell module | FUJIFILM CORP | 2014-12-17 | — | — | CN | disclosed |
| US-8643114-B2 | Semiconductor device and electronic apparatus | SEIKO EPSON CORPORATION (JP) | 2014-02-04 | — | — | US | disclosed |
| US-20100327282-A1 | SEMICONDUCTOR DEVICE AND ELECTRONIC APPARATUS | SEIKO EPSON CORPORATION (JP) | 2010-12-30 | — | — | US | disclosed |
| CN-1332791-C | Natural products composites | CIBA SC HOLDING AG (CH) | 2007-08-22 | — | — | CN | disclosed |
| CN-1777494-A | natural product complex | CIBA SC HOLDING AG (CH) | 2006-05-24 | — | — | CN | disclosed |
| EP-0669358-B1 | BIODEGRADABLE COPOLYESTER, MOLDING PRODUCED THEREFROM, AND PROCESS FOR PRODUCING THE MOLDING | KANEBO LTD (JP) | 2003-11-19 | — | — | EP | disclosed |
| US-5593778-A | FIBERS, FABRICS, LACTIC ACID, POLYETHYLENE GLYCOL, A DICARBOXYPHENYL SULFONATE MONOMER | KANEBO, LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0669358-A1 | BIODEGRADABLE COPOLYESTER, MOLDING PRODUCED THEREFROM, AND PROCESS FOR PRODUCING THE MOLDING | KANEBO LTD. (JP) | 1995-08-30 | — | — | EP | disclosed |