⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18866637 | 0.79 | — | — | |
| SCHEMBL19174674 | 0.79 | — | — | |
| SCHEMBL8677271 | 0.78 | — | — | |
| Butane SCHEMBL10485249 | 0.72 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL18844529 | 0.69 | — | — | |
| SCHEMBL1275854 | 0.68 | — | — | |
| SCHEMBL20124852 | 0.68 | — | — | |
| SCHEMBL9680409 | 0.68 | — | — | |
| SCHEMBL20124842 | 0.68 | — | — | |
| SCHEMBL23734197 | 0.67 | LMNA (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10336785-B2 | Methods for synthesizing nucleotide analogues with disulfide linkers | QIAGEN SCIENCES, LLC (US) | 2019-07-02 | — | — | US | disclosed |
| US-10301346-B2 | Nucleotide analogues | QIAGEN SCIENCES, LLC (US) | 2019-05-28 | — | — | US | disclosed |
| US-20170137869-A1 | METHODS FOR SYNTHESIZING NUCLEOTIDE ANALOGUES WITH DISULFIDE LINKERS | IsoPlexis Corporation | 2017-05-18 | — | — | US | disclosed |
| US-20170130051-A1 | NUCLEOTIDE ANALOGUES | IsoPlexis Corporation | 2017-05-11 | — | — | US | disclosed |