Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25047708 | 0.92 | HDAC3 (0.48) | HDAC3HDAC1HDAC2NCOR2MEN1 | |
| SCHEMBL4781274 | 0.90 | HDAC3 (0.48) | HDAC3HDAC1HDAC2NCOR2MEN1 | |
| SCHEMBL4450404 | 0.89 | BCHE (0.55) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 | |
| SCHEMBL1845666 | 0.88 | MEN1 (0.46) | HDAC3HDAC1HDAC2NCOR2MEN1 | |
| SCHEMBL2260891 | 0.87 | MEN1 (0.45) | HDAC3HDAC1HDAC2NCOR2MEN1 | |
| SCHEMBL9060170 | 0.87 | HDAC1 (0.60) | HDAC3HDAC1HDAC2NCOR2L3MBTL1 | |
| SCHEMBL9823156 | 0.87 | HDAC1 (0.54) | HDAC3HDAC1HDAC2NCOR2MEN1 | |
| SCHEMBL25046666 | 0.86 | L3MBTL1 (0.45) | HDAC3HDAC1HDAC2NCOR2MEN1 | |
| SCHEMBL3050230 | 0.85 | MEN1 (0.46) | HDAC3HDAC1HDAC2NCOR2MEN1 | |
| SCHEMBL25047881 | 0.85 | L3MBTL1 (0.47) | HDAC3HDAC1HDAC2NCOR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017079476-A1 | LSD1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2017-05-11 | — | — | WO | disclosed |