⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL9840618 | 0.92 | HDAC1 (0.84) | — | |
| SCHEMBL1858111 | 0.86 | RAB9A (0.78) | — | |
| SCHEMBL8402365 | 0.86 | HDAC1 (0.75) | — | |
| SCHEMBL27691135 | 0.85 | HDAC1 (0.72) | — | |
| SCHEMBL27923759 | 0.82 | — | — | |
| SCHEMBL2572977 | 0.82 | — | — | |
| SCHEMBL28006263 | 0.82 | — | — | |
| SCHEMBL355263 | 0.82 | — | — | |
| SCHEMBL3074291 | 0.82 | — | — | |
| SCHEMBL77352 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119176819-B | Method for preparing 3, 6-dihydro-1, 2-oxazine derivative by iodine catalysis in aqueous phase | 山东第二医科大学 | 2025-02-14 | — | — | CN | claimed |
| CN-119176819-A | Method for preparing 3, 6-dihydro-1, 2-oxazine derivative by iodine catalysis in aqueous phase | 山东第二医科大学 | 2024-12-24 | — | — | CN | claimed |
| US-11981648-B2 | Method for the synthesis of 3-R-1,4,2-dioxazol-5-ones | TESLA, INC. (US) | 2024-05-14 | — | — | US | claimed |
| US-20230029852-A1 | METHOD FOR THE SYNTHESIS OF 3-R-1,4,2-DIOXAZOL-5-ONES | PANASONIC HOLDINGS CORPORATION (JP) | 2023-02-02 | — | — | US | claimed |
| EP-3624804-B1 | HISTONE DEACETYLASES (HDACS) INHIBITORS | ANNJI PHARM CO LTD (TW) | 2022-02-16 | — | — | EP | claimed |
| US-8546588-B2 | Substituted hydroxamic acids and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2013-10-01 | — | — | US | claimed |
| WO-2005066151-A2 | HISTONE DEACETYLASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2005-07-21 | — | — | WO | claimed |
| EP-0191163-B1 | PROCESS FOR THE PRODUCTION OF THIOLHYDROXAMATES | MAKHTESHIM CHEMICAL WORKS LIMITED (IL) | 1990-05-23 | — | — | EP | claimed |
| CN-119176819-B | Method for preparing 3, 6-dihydro-1, 2-oxazine derivative by iodine catalysis in aqueous phase | 山东第二医科大学 | 2025-02-14 | — | — | CN | disclosed |
| CN-119431189-A | Hydroxamic acid compound and application thereof | 惠州市第一人民医院 | 2025-02-14 | — | — | CN | disclosed |
| CN-119176819-A | Method for preparing 3, 6-dihydro-1, 2-oxazine derivative by iodine catalysis in aqueous phase | 山东第二医科大学 | 2024-12-24 | — | — | CN | disclosed |
| US-20240287008-A1 | METHOD FOR THE SYNTHESIS OF 3-R-1,4,2-DIOXAZOL-5-ONES | PANASONIC HOLDINGS CORPORATION (JP) | 2024-08-29 | — | — | US | disclosed |
| CN-115160097-B | Method for synthesizing amide by reducing N-O bond by thioacetic acid | 温州大学 | 2024-05-28 | — | — | CN | disclosed |
| US-11981648-B2 | Method for the synthesis of 3-R-1,4,2-dioxazol-5-ones | TESLA, INC. (US) | 2024-05-14 | — | — | US | disclosed |
| EP-0191163-B1 | PROCESS FOR THE PRODUCTION OF THIOLHYDROXAMATES | MAKHTESHIM CHEMICAL WORKS LIMITED (IL) | 1990-05-23 | — | — | EP | disclosed |
| US-4886913-A | Process for preparing 2-methyl-2-(methylthio) propionaldehyde O-(methylcarbamoyl) oxime as a water-wet cake | RHONE-POULENC NEDERLAND, B.V. (NL) | 1989-12-12 | — | — | US | disclosed |
| US-4847413-A | Process for preparing 2-methyl-2-(methylsulfonyl) propionaldehyde O-(methylcarbamoyl) oxime as a water-wet cake | RHONE-POULENC NEDERLAND, B.V. (NL) | 1989-07-11 | — | — | US | disclosed |
| CN-87104472-A | The preparation method of the water-wet cake of 2-methyl-2-(methylthio group)-O-(methyl-carbamoyl) propionaldoxime | — | 1988-11-16 | — | — | CN | disclosed |
| EP-0255984-A1 | Process for preparing 2-methyl 2-(methylthio) propionaldehyde 0-(methylcarbamoyl) oxime as a water-wet cake | RHONE POULENC NEDERLAND B.V. (NL) | 1988-02-17 | — | — | EP | disclosed |
| EP-0191163-A2 | Process for the production of thiolhydroxamates | MAKHTESHIM CHEMICAL WORKS LIMITED (IL) | 1986-08-20 | — | — | EP | disclosed |