Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21163755 | 1.00 | NR1H4 (0.57) | NR1H4 | |
| SCHEMBL21163766 | 1.00 | NR1H4 (0.57) | NR1H4 | |
| SCHEMBL22837114 | 1.00 | NR1H4 (0.57) | NR1H4 | |
| SCHEMBL18850503 | 1.00 | NR1H4 (0.57) | NR1H4 | |
| SCHEMBL18850504 | 1.00 | NR1H4 (0.57) | NR1H4 | |
| SCHEMBL15700227 | 1.00 | NR1H4 (0.57) | NR1H4 | |
| SCHEMBL18850601 | 0.94 | NR1H4 (0.57) | NR1H4 | |
| SCHEMBL19413534 | 0.92 | NR1H4 (0.48) | NR1H4 | |
| SCHEMBL15700219 | 0.92 | NR1H4 (0.48) | NR1H4 | |
| SCHEMBL18329761 | 0.87 | NR1H4 (0.68) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10604545-B2 | Methods for the preparation of obeticholic acid and derivatives thereof | INTERCEPT PHARMACEUTICALS, INC. (US) | 2020-03-31 | — | — | US | disclosed |
| WO-2017079062-A1 | METHODS FOR THE PREPARATION OF OBETICHOLIC ACID AND DERIVATIVES THEREOF | INTERCEPT PHARMACEUTICALS, INC. (US) | 2017-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10604545-B2 | Methods for the preparation of obeticholic acid and derivatives thereof | SLC10A1, SLC10A2, TBCA | NR1H4 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.