Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 12/20 | 0.34 |
| ▸ | BCR | P11274 | 12/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | WNT1 | P04628 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18849782 | 1.00 | SCN3A (0.42) | SCN3ASCN9AABL1BCRAAK1 | |
| SCHEMBL18849685 | 0.93 | SCN3A (0.43) | SCN3ASCN9AABL1BCRAAK1 | |
| SCHEMBL18849642 | 0.92 | SCN3A (0.36) | SCN3ASCN9AABL1BCR | |
| SCHEMBL18849675 | 0.90 | SCN3A (0.53) | SCN3ASCN9AAAK1IKBKBCHUK | |
| SCHEMBL28926136 | 0.90 | SCN3A (0.53) | SCN3ASCN9AAAK1IKBKBCHUK | |
| SCHEMBL18849853 | 0.85 | PSMB8 (0.35) | SCN3ASCN9AABL1BCRIKBKB | |
| SCHEMBL18849831 | 0.84 | SCN3A (0.36) | SCN3ASCN9AABL1BCR | |
| SCHEMBL18849651 | 0.84 | SCN3A (0.49) | SCN3ASCN9AABL1BCRAAK1 | |
| SCHEMBL18849650 | 0.84 | SCN3A (0.53) | SCN3ASCN9AAAK1IKBKBCHUK | |
| SCHEMBL28647731 | 0.84 | SCN3A (0.53) | SCN3ASCN9AAAK1IKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017076201-A1 | HCV INHIBITORS, PREPARATION METHOD AND USE THEREOF | 江苏豪森药业集团有限公司 | 2017-05-11 | — | — | WO | disclosed |