Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.53 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.53 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | WNT1 | P04628 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.40 |
| ▸ | IKBKB | O14920 | 2/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
| ▸ | ULK1 | O75385 | 1/20 | 0.37 |
| ▸ | PFKFB2 | O60825 | 2/20 | 0.37 |
| ▸ | PFKFB1 | P16118 | 2/20 | 0.37 |
| ▸ | PFKFB3 | Q16875 | 2/20 | 0.37 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18849675 | 1.00 | SCN3A (0.53) | SCN3ASCN9AAAK1DHODHWNT1 | |
| SCHEMBL28647731 | 0.92 | SCN3A (0.53) | SCN3ASCN9AAAK1DHODHWNT1 | |
| SCHEMBL18849650 | 0.92 | SCN3A (0.53) | SCN3ASCN9AAAK1DHODHWNT1 | |
| SCHEMBL18849782 | 0.90 | SCN3A (0.42) | SCN3ASCN9AAAK1DHODHWNT1 | |
| SCHEMBL18849641 | 0.90 | SCN3A (0.42) | SCN3ASCN9AAAK1DHODHWNT1 | |
| SCHEMBL18849750 | 0.88 | SCN3A (0.56) | SCN3ASCN9AAAK1DHODHWNT1 | |
| SCHEMBL28651738 | 0.88 | SCN3A (0.56) | SCN3ASCN9AAAK1DHODHWNT1 | |
| SCHEMBL205890 | 0.86 | SCN3A (0.70) | SCN3ASCN9AAAK1DHODHWNT1 | |
| SCHEMBL2709126 | 0.86 | SCN3A (0.70) | SCN3ASCN9AAAK1DHODHWNT1 | |
| SCHEMBL204893 | 0.84 | SCN3A (0.57) | SCN3ASCN9AAAK1DHODHWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108349945-B | HCV inhibitor, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2021-10-29 | — | — | CN | disclosed |