Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1884977 | 0.84 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL10897745 | 0.78 | TSHR (0.38) | — | |
| SCHEMBL453990 | 0.74 | — | — | |
| SCHEMBL1352111 | 0.72 | — | — | |
| SCHEMBL10882223 | 0.72 | ALDH1A1 (0.32) | HCAR2 | |
| SCHEMBL7901991 | 0.70 | TP53 (0.35) | MEN1KMT2A | |
| Ethylene Glycol SCHEMBL4357944 | 0.70 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL9544225 | 0.68 | HCAR2 (0.32) | HCAR2 | |
| Propene SCHEMBL4353692 | 0.67 | HCAR2 (0.44) | HCAR2 | |
| SCHEMBL9386810 | 0.67 | TSHR (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8492510-B2 | Multifunctional degradable nanoparticles with control over size and functionalities | VANDERBILT UNIVERSITY (US) | 2013-07-23 | — | — | US | disclosed |
| WO-2011082432-A1 | MULTIFUNCTIONAL DEGRADABLE NANOPARTICLES WITH CONTROL OVER SIZE AND FUNCTIONALITIES | VANDERBILT UNIVERSITY (US) | 2011-07-07 | — | — | WO | disclosed |
| US-7935782-B2 | Multifunctional degradable nanoparticles with control over size and functionalities | VANDERBILT UNIVERSITY (US) | 2011-05-03 | — | — | US | disclosed |