Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18960605 | 0.85 | KMT2A (0.39) | CACNA1DALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL16850477 | 0.85 | ALDH1A1 (0.37) | CACNA1DALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL20733752 | 0.83 | ALDH1A1 (0.33) | CACNA1DALDH1A1HPGDRXFP1TSHR | |
| SCHEMBL18786172 | 0.82 | ALDH1A1 (0.43) | CACNA1DALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL17905821 | 0.82 | TNKS2 (0.37) | TNKS2ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL17905911 | 0.81 | — | — | |
| SCHEMBL17905819 | 0.80 | — | — | |
| SCHEMBL18965405 | 0.80 | ALDH1A1 (0.33) | ALDH1A1HPGDTSHRHSD17B10CYP1A2 | |
| SCHEMBL20733760 | 0.80 | ALDH1A1 (0.37) | CACNA1DALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL18731711 | 0.80 | CYP1A2 (0.38) | TNKS2CACNA1DALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017078182-A1 | BENZIMIDAZOLE FUSED HETEROARYLS | IDEMITSU KOSAN CO., LTD. (JP) | 2017-05-11 | — | — | WO | disclosed |