SCHEMBL18854259

SCHEMBL18854259

Cc1cc2sc(I)nc2s1

nearest known ligand 0.31

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
MAPT P10636 1/20 0.31
PKM P14618 1/20 0.31
HPGD P15428 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25804146 0.79
SCHEMBL2607101 0.77 SMN1; SMN2 (0.48) NPC1ALDH1A1TP53MAPTPKM
SCHEMBL10790337 0.74 ALDH1A1 (0.48) NPC1ALDH1A1TP53MAPTRAB9A
SCHEMBL16329817 0.71 NPC1 (0.53) NPC1RAB9A
SCHEMBL15896715 0.71 CASR (0.30)
SCHEMBL16479943 0.71 CASR (0.32)
SCHEMBL19214697 0.68 ALDH1A1 (0.34) NPC1ALDH1A1TP53MAPTPKM
SCHEMBL18826119 0.68 MAPT (0.34) NPC1ALDH1A1MAPTPKMRAB9A
SCHEMBL19997104 0.67 SRC (0.35)
SCHEMBL19504300 0.67 SMN1; SMN2 (0.46) NPC1ALDH1A1TP53MAPTPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200264460-A1 POLARIZING PLATE AND CIRCULARLY POLARIZING PLATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-08-20 US disclosed
US-10690953-B2 Polarizing plate and circularly polarizing plate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-06-23 US disclosed
US-10270034-B2 Tetra-aryl indacenodithiophene-based polycyclic polymers and their use MERCK PATENT GMBH (DE) 2019-04-23 US disclosed
US-20180067348-A1 POLARIZING PLATE AND CIRCULARLY POLARIZING PLATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-03-08 US disclosed
US-20170141317-A1 TETRA-ARYL INDACENODITHIOPHENE-BASED POLYCYCLIC POLYMERS AND THEIR USE MERCK PATENT GMBH (DE) 2017-05-18 US disclosed