SCHEMBL18854948

SCHEMBL18854948

CC[S+]([O-])c1ccc(-n2cncn2)nc1-c1nc2cc(C)cnc2n1C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.30
▸ POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18866375 0.88 POLB (0.37) POLB
SCHEMBL18854947 0.85 — —
SCHEMBL18854946 0.85 — —
SCHEMBL18854950 0.83 — —
SCHEMBL18854949 0.83 — —
SCHEMBL18854919 0.82 BRD4 (0.35) —
SCHEMBL18854945 0.81 BRD4 (0.34) —
SCHEMBL18854940 0.80 KDM4E (0.31) KDM4EPOLB
SCHEMBL24286101 0.80 ALOX5AP (0.30) —
SCHEMBL18854927 0.80 KDM4E (0.32) KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9668482-B1 Fused heterocyclic compound and pest control application thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-06 — — US disclosed
US-20170135348-A1 FUSED HETEROCYCLIC COMPOUND AND PEST CONTROL APPLICATION THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-05-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170135348-A1 FUSED HETEROCYCLIC COMPOUND AND PEST CONTROL APPLICATION THEREOF KEAP1, DDT, CYP4B1 KDM4E 1289/4885POLB 4756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback