SCHEMBL18855474

SCHEMBL18855474

CSSCO[C@H]1CC(n2ccc(=O)[nH]c2=O)OC1COP(=O)(O)OP(=O)(O)OP(=O)(O)O

nearest known ligand 0.59

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 16/20 0.59
P2RY4 P51582 11/20 0.59
POLA1 P09884 1/20 0.53
P2RY6 Q15077 7/20 0.53
DUT P33316 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19174701 1.00 P2RY2 (0.59) P2RY2P2RY4POLA1P2RY6DUT
SCHEMBL23734157 0.91 P2RY2 (0.56) P2RY2P2RY4POLA1P2RY6DUT
SCHEMBL24905837 0.91 P2RY2 (0.56) P2RY2P2RY4POLA1P2RY6DUT
SCHEMBL18844356 0.88 DUT (0.47) P2RY2P2RY4P2RY6DUT
SCHEMBL24023167 0.86 POLB (0.66) POLA1
SCHEMBL18840574 0.86 POLB (0.66) POLA1
SCHEMBL23434907 0.86 POLB (0.66) POLA1
SCHEMBL27341456 0.84 P2RY2 (0.58) P2RY2P2RY4POLA1P2RY6DUT
SCHEMBL23585777 0.84 P2RY2 (0.58) P2RY2P2RY4POLA1P2RY6DUT
SCHEMBL30523091 0.84 P2RY2 (0.61) P2RY2P2RY4POLA1P2RY6DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170137878-A1 METHODS OF USING NUCLEOTIDE ANALOGUES IsoPlexis Corporation 2017-05-18 US disclosed