Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18855535 | 0.85 | DRD1 (0.31) | — | |
| SCHEMBL1935366 | 0.73 | L3MBTL1 (0.47) | — | |
| SCHEMBL18855569 | 0.72 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL18855573 | 0.72 | AURKA (0.44) | — | |
| SCHEMBL18855950 | 0.67 | — | — | |
| SCHEMBL18855935 | 0.67 | ABL1 (0.37) | SMN1; SMN2 | |
| SCHEMBL24243000 | 0.66 | — | — | |
| SCHEMBL18855873 | 0.64 | — | — | |
| SCHEMBL24243062 | 0.63 | IKBKB (0.30) | — | |
| SCHEMBL21470789 | 0.62 | MGAM (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3950692-A1 | NOVEL TRICYCLIC COMPOUNDS | AbbVie Inc. (US) | 2022-02-09 | — | — | EP | disclosed |
| EP-2506716-B1 | NOVEL TRICYCLIC COMPOUNDS | ABBVIE INC (US) | 2017-05-17 | — | — | EP | disclosed |