Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18855510 | 0.90 | L3MBTL1 (0.50) | L3MBTL1ALDH3A1NOD1POLBHTT | |
| SCHEMBL27893073 | 0.86 | L3MBTL1 (0.53) | L3MBTL1ALDH3A1NOD1POLBHTT | |
| Hydrochloric Acid SCHEMBL27838799 | 0.84 | L3MBTL1 (0.52) | L3MBTL1ALDH3A1NOD1POLBHTT | |
| SCHEMBL1934124 | 0.84 | L3MBTL1 (0.47) | L3MBTL1ALDH3A1NOD1POLBHTT | |
| SCHEMBL26451130 | 0.83 | L3MBTL1 (0.51) | L3MBTL1ALDH3A1NOD1POLBHTT | |
| SCHEMBL1536134 | 0.83 | L3MBTL1 (0.51) | L3MBTL1ALDH3A1NOD1POLBHTT | |
| SCHEMBL18855429 | 0.83 | L3MBTL1 (0.46) | L3MBTL1ALDH3A1NOD1POLBHTT | |
| SCHEMBL14795013 | 0.83 | L3MBTL1 (0.46) | L3MBTL1ALDH3A1NOD1POLBHTT | |
| Formic Acid SCHEMBL27873518 | 0.83 | L3MBTL1 (0.46) | L3MBTL1ALDH3A1NOD1POLBHTT | |
| SCHEMBL4348950 | 0.81 | L3MBTL1 (0.49) | L3MBTL1ALDH3A1NOD1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3950692-A1 | NOVEL TRICYCLIC COMPOUNDS | AbbVie Inc. (US) | 2022-02-09 | — | — | EP | disclosed |
| EP-2506716-B1 | NOVEL TRICYCLIC COMPOUNDS | ABBVIE INC (US) | 2017-05-17 | — | — | EP | disclosed |