Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | EED | O75530 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20684438 | 0.89 | L3MBTL1 (0.48) | L3MBTL1ALDH3A1POLBHTTNOD1 | |
| SCHEMBL2318672 | 0.87 | L3MBTL1 (0.46) | L3MBTL1ALDH3A1POLBHTTNOD1 | |
| SCHEMBL2317967 | 0.87 | L3MBTL1 (0.46) | L3MBTL1ALDH3A1POLBHTTNOD1 | |
| SCHEMBL18855958 | 0.86 | L3MBTL1 (0.46) | L3MBTL1ALDH3A1POLBHTTNOD1 | |
| SCHEMBL2359779 | 0.85 | L3MBTL1 (0.45) | L3MBTL1ALDH3A1POLBHTTNOD1 | |
| SCHEMBL1934188 | 0.85 | L3MBTL1 (0.51) | L3MBTL1ALDH3A1POLBHTTNOD1 | |
| SCHEMBL13579594 | 0.85 | L3MBTL1 (0.51) | L3MBTL1ALDH3A1POLBHTTNOD1 | |
| SCHEMBL1536777 | 0.85 | L3MBTL1 (0.51) | L3MBTL1ALDH3A1POLBHTTNOD1 | |
| Hydrochloric Acid SCHEMBL1536094 | 0.84 | L3MBTL1 (0.50) | L3MBTL1ALDH3A1POLBHTTNOD1 | |
| SCHEMBL1536172 | 0.83 | L3MBTL1 (0.49) | L3MBTL1ALDH3A1POLBHTTNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2506716-B1 | NOVEL TRICYCLIC COMPOUNDS | ABBVIE INC (US) | 2017-05-17 | — | — | EP | disclosed |