Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASGR1 | P07306 | 10/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17268935 | 0.93 | ASGR1 (0.43) | ASGR1 | |
| SCHEMBL18968191 | 0.92 | ASGR1 (0.42) | ASGR1 | |
| SCHEMBL17256367 | 0.89 | ASGR1 (0.40) | ASGR1 | |
| SCHEMBL17268938 | 0.88 | ASGR1 (0.41) | ASGR1 | |
| SCHEMBL21500344 | 0.85 | ASGR1 (0.37) | ASGR1 | |
| SCHEMBL24724923 | 0.84 | ASGR1 (0.43) | ASGR1 | |
| SCHEMBL17256431 | 0.79 | ASGR1 (0.56) | ASGR1 | |
| SCHEMBL17256429 | 0.79 | ASGR1 (0.67) | ASGR1 | |
| SCHEMBL21956056 | 0.79 | ASGR1 (0.51) | ASGR1 | |
| SCHEMBL27228129 | 0.79 | ASGR1 (0.51) | ASGR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017083368-A9 | TISSUE-SPECIFIC GENOME ENGINEERING USING CRISPR-CAS9 | PFIZER INC. (US) | 2018-04-12 | — | — | WO | disclosed |
| WO-2017083368-A1 | TISSUE-SPECIFIC GENOME ENGINEERING USING CRISPR-CAS9 | PFIZER INC. (US) | 2017-05-18 | — | — | WO | disclosed |