Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASGR1 | P07306 | 14/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17268935 | 0.86 | ASGR1 (0.43) | ASGR1 | |
| SCHEMBL21500344 | 0.86 | ASGR1 (0.37) | ASGR1 | |
| SCHEMBL18857379 | 0.84 | ASGR1 (0.48) | ASGR1 | |
| SCHEMBL18968191 | 0.83 | ASGR1 (0.42) | ASGR1 | |
| SCHEMBL23346073 | 0.82 | ASGR1 (0.62) | ASGR1 | |
| SCHEMBL17256367 | 0.81 | ASGR1 (0.40) | ASGR1 | |
| SCHEMBL26878623 | 0.80 | ASGR1 (0.35) | ASGR1 | |
| SCHEMBL17268938 | 0.80 | ASGR1 (0.41) | ASGR1 | |
| SCHEMBL26899494 | 0.79 | HCRTR2 (0.39) | ASGR1HCRTR2 | |
| SCHEMBL26899410 | 0.78 | NFKB1 (0.37) | ASGR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022235699-A2 | POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |
| US-9610368-B2 | Radiolabelled glutaminyl cyclase (QC) inhibitors and uses of same | PROBIODRUG AG (DE) | 2017-04-04 | — | — | US | disclosed |