Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.40 |
| ▸ | KDM6B | O15054 | 4/20 | 0.40 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.40 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.37 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18858140 | 0.87 | HDAC1 (0.43) | KDM4CKDM6BKDM4D | |
| SCHEMBL18858141 | 0.87 | HDAC1 (0.47) | — | |
| SCHEMBL18858143 | 0.80 | HDAC1 (0.35) | KDM4CKDM6BKDM4DEGLN3KDM5A | |
| SCHEMBL5767632 | 0.78 | NOTUM (0.57) | NOTUMALDH1A1POLBSMN1; SMN2GAA | |
| SCHEMBL18858139 | 0.74 | KDM4C (0.40) | KDM4CKDM6BKDM4DEGLN3GALR3 | |
| SCHEMBL9413722 | 0.70 | KDM4C (0.46) | KDM4CKDM6BKDM4DEGLN3KDM4E | |
| SCHEMBL5913077 | 0.70 | HPGD (0.57) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL6068705 | 0.69 | GAA (0.65) | KDM4EALDH1A1POLBSMN1; SMN2GAA | |
| SCHEMBL10338664 | 0.69 | KDM4C (0.47) | KDM4CKDM6BKDM4DALDH1A1POLB | |
| SCHEMBL11785889 | 0.68 | ALDH1A1 (0.64) | KDM4EALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180134662-A1 | Aminopyridine Based Buffers with Wide Buffering Ranges Antibiotics and Myelin Disease Therapy | TPAT IP LLC | 2018-05-17 | — | — | US | disclosed |
| US-9867813-B2 | Aminopyridine based buffers with wide buffering ranges, antibiotics and myelin disease therapy | TPAT IP LLC | 2018-01-16 | — | — | US | disclosed |
| US-20170135998-A1 | Aminopyridine Based Buffers with Wide Buffering Ranges, Antibiotics and Myelin Disease Therapy | TPAT IP LLC | 2017-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134662-A1 | Aminopyridine Based Buffers with Wide Buffering Ranges Antibiotics and Myelin Disease Therapy | AQP4, PMP22, MAG | KDM4C 2547/4885KDM6B 2035/4885KDM4D 1782/4885 |
| US-20170135998-A1 | Aminopyridine Based Buffers with Wide Buffering Ranges, Antibiotics and Myelin Disease Therapy | AQP4, PMP22, MAG | KDM4C 2583/4885KDM6B 2054/4885KDM4D 1904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.