Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18858136 | 0.89 | MAPK8 (0.39) | HDAC3HDAC1MAPK8MAPK9MAPK10 | |
| SCHEMBL18858139 | 0.87 | KDM4C (0.40) | KDM6BKDM4DKDM4CCA1CA2 | |
| SCHEMBL18858144 | 0.79 | MAPK8 (0.34) | MAPK8MAPK9MAPK10KDM6BKDM4D | |
| SCHEMBL18858141 | 0.76 | HDAC1 (0.47) | HDAC3HDAC1HDAC2 | |
| SCHEMBL17095493 | 0.72 | HDAC3 (0.49) | HDAC3HDAC1KDM4EALDH1A1MAPT | |
| SCHEMBL28824138 | 0.72 | KDM4E (0.53) | HDAC3HDAC1HDAC2KDM4EALDH1A1 | |
| SCHEMBL9426430 | 0.71 | KDM4E (0.50) | HDAC3HDAC1HDAC2KDM4EALDH1A1 | |
| SCHEMBL15432244 | 0.68 | KDM4E (0.56) | HDAC3HDAC1HDAC2KDM4EALDH1A1 | |
| SCHEMBL8252207 | 0.67 | MAPT (0.43) | HDAC3HDAC1KDM4EALDH1A1MEN1 | |
| SCHEMBL16095414 | 0.67 | PTPN1 (0.48) | HDAC3HDAC1HDAC2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170135998-A1 | Aminopyridine Based Buffers with Wide Buffering Ranges, Antibiotics and Myelin Disease Therapy | TPAT IP LLC | 2017-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170135998-A1 | Aminopyridine Based Buffers with Wide Buffering Ranges, Antibiotics and Myelin Disease Therapy | AQP4, PMP22, MAG | HDAC3 2650/4885HDAC1 2464/4885MAPK8 3665/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.