Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KDM6B | O15054 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14357917 | 0.85 | HDAC1 (0.46) | KDM4EALDH1A1GLAGAAMEN1 | |
| Hydrochloric Acid SCHEMBL29373586 | 0.84 | HDAC1 (0.45) | KDM4EALDH1A1GLAGAAMEN1 | |
| Hydrochloric Acid SCHEMBL5749683 | 0.84 | HDAC1 (0.45) | KDM4EALDH1A1GLAGAAMEN1 | |
| SCHEMBL28824138 | 0.83 | KDM4E (0.53) | KDM4EALDH1A1GLAGAAMEN1 | |
| SCHEMBL10338664 | 0.82 | KDM4C (0.47) | ALDH1A1GAAMEN1KDM6BMAPT | |
| SCHEMBL15432244 | 0.82 | KDM4E (0.56) | KDM4EALDH1A1GLAGAAMEN1 | |
| SCHEMBL1430982 | 0.81 | HDAC1 (0.46) | ALDH1A1MAPTHDAC1HDAC6CHUK | |
| SCHEMBL3787548 | 0.81 | CA1 (0.49) | KDM4EALDH1A1GLAGAAMEN1 | |
| SCHEMBL15432239 | 0.80 | XIAP (0.45) | KDM4EALDH1A1GLAGAAMEN1 | |
| SCHEMBL4139383 | 0.79 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2AKDM4CTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371086-A | Circulatory disorders side effect reduction | THE GREEN CROSS CORPORATION (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5262415-A | FOR TREATING DISEASES OF THE CIRCULATORY SYSTEM | THE GREEN CROSS CORPORATION (JP) | 1993-11-16 | — | — | US | disclosed |
| EP-0503627-A1 | Aminopyridine compounds | THE GREEN CROSS CORPORATION (JP) | 1992-09-16 | — | — | EP | disclosed |