SCHEMBL1885835

SCHEMBL1885835

C=CCN(CC=C)c1ccc(Cc2ccc(N(CC=C)CC=C)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHKA P35790 1/20 0.51
ALDH1A1 P00352 3/20 0.50
CYP3A4 P08684 2/20 0.50
TSHR P16473 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
MAPK1 P28482 1/20 0.50
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38
PYCR1 P32322 1/20 0.37
ALDH3A1 P30838 1/20 0.34
ALDH1A3 P47895 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
GAA P10253 1/20 0.33
PTPN1 P18031 2/20 0.32
DHFR P00374 2/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6140286 0.90 CYP3A4 (0.52) CHKAALDH1A1CYP3A4TSHRTDP1
SCHEMBL851567 0.88 CHKA (0.50) CHKAALDH1A1CYP3A4TSHRTDP1
SCHEMBL7162904 0.81 CHKA (0.46) CHKAALDH1A1CYP3A4TSHRTDP1
SCHEMBL6466250 0.81 CHKA (0.46) CHKAALDH1A1CYP3A4TSHRTDP1
SCHEMBL6692403 0.81 CHKA (0.46) CHKAALDH1A1CNR1CNR2PYCR1
SCHEMBL15794089 0.79 CHKA (0.54) CHKAALDH1A1TSHRTDP1CNR1
SCHEMBL19886353 0.79 CHKA (0.40) CHKAALDH1A1CYP3A4TSHRTDP1
SCHEMBL16641014 0.79 CHKA (0.37) CHKAALDH1A1CYP3A4TSHRTDP1
SCHEMBL11301507 0.79 CHKA (0.40) CHKAALDH1A1CYP3A4TSHRTDP1
SCHEMBL5611650 0.79 ALDH1A1 (0.52) CHKAALDH1A1CYP3A4TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 374 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9012517-A None JP disclosed
CN-110831778-B Near Infrared (NIR) laser markable compositions 爱克发有限公司 2022-07-01 CN disclosed
EP-3928995-A1 MARKING OF ARTICLES AGFA NV (BE) 2021-12-29 EP disclosed
EP-3928996-A1 MARKING OF ARTICLES AGFA NV (BE) 2021-12-29 EP disclosed
EP-3838609-A1 LASER MARKABLE ARTICLES AGFA NV (BE) 2021-06-23 EP disclosed
EP-3838610-A1 LASER MARKABLE ARTICLES AGFA NV (BE) 2021-06-23 EP disclosed
US-20210019584-A1 A LASER MARKABLE RFID TAG AGFA NV (BE) 2021-01-21 US disclosed
US-10853712-B2 Authentication method of a two dimensional bar code AGFA NV (BE) 2020-12-01 US disclosed
US-10837909-B2 Super-resolution fluorescent imaging probe THE UNIVERSITY OF TOKYO (JP) 2020-11-17 US disclosed
US-20200238246-A1 A COMPOSITION COMPRISING SOLVENT AND HEAT RESISTANT CAPSULES AGFA NV (BE) 2020-07-30 US disclosed
US-4463079-A Heat developable color photographic materials with redox dye releasers FUJI PHOTO FILM CO., LTD. (JP) 1984-07-31 US disclosed
US-4455363-A Heat-developable color photographic material with polymeric color coupler FUJI PHOTO FILM CO., LTD. (JP) 1984-06-19 US disclosed
EP-0106357-A2 Heat-developable color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1984-04-25 EP disclosed
EP-0106211-A2 Heat developable color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1984-04-25 EP disclosed
US-4430415-A Heat-developable photographic material with fine droplets containing silver halide, organic silver salt oxidizing agent and color image forming substance FUJI PHOTO FILM CO., LTD. (JP) 1984-02-07 US disclosed
EP-0079056-A2 Heat-developable color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1983-05-18 EP disclosed
EP-0076492-A2 Heat-developable color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1983-04-13 EP disclosed
EP-0067455-A1 Heat-developable color photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1982-12-22 EP disclosed
EP-0066282-A1 Heat-developable color photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1982-12-08 EP disclosed
US-3755310-A SUBSTITUTED BIS(P-DIALKYLAMINOPHENYL)METHANE PHOTOCONDUCTORS EASTMAN KODAK CO 1973-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10837909-B2 Super-resolution fluorescent imaging probe CBR3, CNKSR1, CBR1 CHKA 1830/4885ALDH1A1 1731/4885CYP3A4 2794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.