Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8402198 | 0.90 | HIF1A (0.55) | KMT2AMAPTMEN1ALDH1A1TP53 | |
| SCHEMBL18705910 | 0.87 | HIF1A (0.51) | KMT2AMAPTMEN1ALDH1A1TP53 | |
| SCHEMBL376300 | 0.84 | HIF1A (0.61) | KMT2AMAPTMEN1ALDH1A1TP53 | |
| SCHEMBL815171 | 0.84 | ALDH1A1 (0.76) | KMT2AMAPTMEN1ALDH1A1TP53 | |
| SCHEMBL12164629 | 0.84 | HTT (0.48) | KMT2AMAPTMEN1ALDH1A1TP53 | |
| SCHEMBL12045495 | 0.84 | MAPT (0.67) | KMT2AMAPTMEN1ALDH1A1TP53 | |
| SCHEMBL17666783 | 0.83 | KMT2A (0.65) | KMT2AMAPTMEN1ALDH1A1TP53 | |
| SCHEMBL10335523 | 0.82 | KMT2A (0.49) | KMT2AMAPTMEN1ALDH1A1TP53 | |
| SCHEMBL18133551 | 0.82 | ALDH1A1 (0.56) | KMT2AMAPTMEN1ALDH1A1TP53 | |
| SCHEMBL7915436 | 0.82 | ALDH1A1 (0.56) | KMT2AMAPTMEN1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9650468-B2 | Encapsulation of active agents for on-demand release | SOUTHWEST RESEARCH INSTITUTE (US) | 2017-05-16 | — | — | US | disclosed |
| US-9650468-B2 | Encapsulation of active agents for on-demand release | SOUTHWEST RESEARCH INSTITUTE (US) | 2017-05-16 | — | — | US | disclosed |