Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16035402 | 0.85 | P2RX7 (0.62) | P2RX7CYP2C19 | |
| SCHEMBL16035401 | 0.85 | P2RX7 (0.62) | P2RX7CYP2C19 | |
| SCHEMBL16089652 | 0.81 | P2RX7 (0.79) | P2RX7CYP2C19 | |
| SCHEMBL16089651 | 0.81 | P2RX7 (0.80) | P2RX7CYP2C19 | |
| SCHEMBL16035723 | 0.81 | P2RX7 (1.00) | P2RX7CYP2C19 | |
| SCHEMBL16089650 | 0.81 | P2RX7 (0.80) | P2RX7CYP2C19 | |
| SCHEMBL16035721 | 0.81 | P2RX7 (1.00) | P2RX7CYP2C19 | |
| SCHEMBL16089646 | 0.81 | P2RX7 (0.80) | P2RX7CYP2C19 | |
| SCHEMBL16089662 | 0.81 | P2RX7 (0.79) | P2RX7CYP2C19 | |
| SCHEMBL16035604 | 0.80 | P2RX7 (1.00) | P2RX7CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970267-B3 | P2X7 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-30 | — | — | EP | disclosed |
| EP-3239151-A1 | P2X7 MODULATORS | Janssen Pharmaceutica NV (BE) | 2017-11-01 | — | — | EP | disclosed |
| EP-2970267-B1 | P2X7 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2017-05-24 | — | — | EP | disclosed |