Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 18/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18861235 | 1.00 | FYN (0.47) | FYNTGFBR1CHEK2CHEK1 | |
| SCHEMBL18861280 | 0.88 | FYN (0.57) | FYNTGFBR1CHEK2CHEK1 | |
| SCHEMBL23158627 | 0.88 | FYN (0.49) | FYNTGFBR1CHEK2CHEK1 | |
| SCHEMBL23158856 | 0.88 | FYN (0.49) | FYNTGFBR1CHEK2CHEK1 | |
| SCHEMBL15334326 | 0.85 | FYN (0.60) | FYNTGFBR1CHEK2CHEK1 | |
| SCHEMBL29631737 | 0.85 | FYN (0.60) | FYNTGFBR1CHEK2CHEK1 | |
| SCHEMBL23158725 | 0.80 | FYN (0.46) | FYNTGFBR1CHEK2CHEK1 | |
| SCHEMBL18861171 | 0.79 | FYN (0.46) | FYNTGFBR1CHEK2CHEK1 | |
| SCHEMBL18861104 | 0.78 | TGFBR1 (0.70) | FYNTGFBR1CHEK2CHEK1 | |
| SCHEMBL18861081 | 0.77 | CHEK2 (0.55) | FYNTGFBR1CHEK2CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3168219-A1 | PYRIDONE DERIVATIVE HAVING TETRAHYDROPYRANYL METHYL GROUP | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-05-17 | — | — | EP | disclosed |