Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 5/20 | 0.55 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.51 |
| ▸ | KISS1R | Q969F8 | 4/20 | 0.51 |
| ▸ | MMP2 | P08253 | 9/20 | 0.50 |
| ▸ | MMP1 | P03956 | 2/20 | 0.50 |
| ▸ | MMP9 | P14780 | 8/20 | 0.49 |
| ▸ | MMP8 | P22894 | 7/20 | 0.49 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.49 |
| ▸ | ADAM12 | O43184 | 1/20 | 0.49 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | MMP7 | P09237 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | MMP15 | P51511 | 1/20 | 0.49 |
| ▸ | MMP16 | P51512 | 1/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.49 |
| ▸ | ADAM9 | Q13443 | 1/20 | 0.49 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18857607 | 0.82 | ECE1 (0.64) | ECE1ERAP2 | |
| SCHEMBL18862464 | 0.82 | GHSR (0.62) | ECE1KISS1RGHSR | |
| SCHEMBL18862366 | 0.78 | GHSR (0.60) | ECE1KISS1RGHSR | |
| SCHEMBL15791257 | 0.77 | ACE (0.62) | ECE1ERAP2 | |
| SCHEMBL15692398 | 0.76 | ECE1 (0.68) | ECE1ERAP2MMP2MMP1MMP9 | |
| SCHEMBL22042954 | 0.76 | ECE1 (0.69) | ECE1ERAP2MMP2MMP1MMP9 | |
| SCHEMBL22042951 | 0.76 | ECE1 (0.69) | ECE1ERAP2MMP2MMP1MMP9 | |
| SCHEMBL23370296 | 0.76 | ECE1 (0.51) | ECE1ERAP2KISS1RMMP2MMP1 | |
| SCHEMBL15692405 | 0.74 | ECE1 (0.71) | ECE1ERAP2 | |
| SCHEMBL9822645 | 0.74 | ECE1 (0.68) | ECE1ERAP2MMP2MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170137801-A1 | TISSUE-SPECIFIC GENOME ENGINEERING USING CRISPR-CAS9 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-05-18 | — | — | US | disclosed |