Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 17/20 | 0.37 |
| ▸ | BIRC3 | Q13489 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18862728 | 0.88 | MALT1 (0.46) | MALT1BIRC3HTR7TMEM97SIGMAR1 | |
| SCHEMBL17292962 | 0.87 | MALT1 (0.40) | MALT1BIRC3HTR7TMEM97SIGMAR1 | |
| SCHEMBL17292964 | 0.87 | MALT1 (0.40) | MALT1BIRC3HTR7TMEM97SIGMAR1 | |
| SCHEMBL17293001 | 0.79 | MALT1 (0.41) | MALT1BIRC3NPC1RAB9AHTR7 | |
| SCHEMBL19826562 | 0.78 | MALT1 (0.44) | MALT1BIRC3HTR7TMEM97SIGMAR1 | |
| SCHEMBL17293075 | 0.76 | MALT1 (0.49) | MALT1BIRC3MEN1NPC1GAA | |
| SCHEMBL17293077 | 0.76 | MALT1 (0.49) | MALT1BIRC3MEN1NPC1GAA | |
| SCHEMBL17293032 | 0.75 | MALT1 (0.51) | MALT1BIRC3HTR7TMEM97SIGMAR1 | |
| SCHEMBL17293034 | 0.75 | MALT1 (0.51) | MALT1BIRC3HTR7TMEM97SIGMAR1 | |
| SCHEMBL25870146 | 0.70 | MALT1 (0.40) | MALT1BIRC3HTR7TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017081641-A1 | NOVEL PYRAZOLO PYRIMIDINE DERIVATIVES | NOVARTIS AG (CH) | 2017-05-18 | — | — | WO | disclosed |