SCHEMBL1886382

SCHEMBL1886382

C=C(C(=O)O)C(N)CCCCC

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.50
GRIK2 Q13002 2/20 0.50
SLC1A2 P43004 2/20 0.50
SLC1A1 P43005 2/20 0.50
DPP7 Q9UHL4 1/20 0.46
GPR84 Q9NQS5 6/20 0.44
FFAR1 O14842 1/20 0.44
GNAI3 P08754 1/20 0.44
GNAO1 P09471 1/20 0.44
GNAI1 P63096 1/20 0.44
SLC1A3 P43003 1/20 0.43
LAP3 P28838 2/20 0.42
MAPT P10636 1/20 0.42
TP53 P04637 1/20 0.42
LCK P06239 1/20 0.42
PPARD Q03181 1/20 0.42
ZDHHC20 Q5W0Z9 1/20 0.42
ZDHHC2 Q9UIJ5 1/20 0.42
SLC15A1 P46059 1/20 0.42
OPRM1 P35372 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1883990 0.98 GRIK1 (0.49) GRIK1GRIK2SLC1A2SLC1A1DPP7
SCHEMBL523166 0.94 SLC1A2 (0.48) GRIK1GRIK2SLC1A2SLC1A1DPP7
SCHEMBL4280235 0.85 GRIK1 (0.45) GRIK1GRIK2SLC1A2SLC1A1DPP7
SCHEMBL5084412 0.84 GRIK1 (0.46) GRIK1GRIK2SLC1A2SLC1A1DPP7
SCHEMBL9421724 0.79 GPR84 (0.47) GRIK1GRIK2SLC1A2SLC1A1GPR84
SCHEMBL3321348 0.79 GRIK1 (0.48) GRIK1GRIK2SLC1A2SLC1A1GPR84
SCHEMBL38735 0.79 GRIK1 (0.68) GRIK1GRIK2SLC1A2SLC1A1GPR84
SCHEMBL5967305 0.79 GRIK1 (0.68) GRIK1GRIK2SLC1A2SLC1A1GPR84
SCHEMBL2730539 0.79 GRIK1 (0.68) GRIK1GRIK2SLC1A2SLC1A1GPR84
Acetic Acid SCHEMBL7107582 0.78 GRIK1 (0.49) GRIK1GRIK2SLC1A2SLC1A1DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8568962-B2 Process for preparing a polymeric relief structure STICHTING DUTCH POLYMER INSTITUTE (NL) 2013-10-29 US disclosed
US-20110104445-A1 PROCESS FOR PREPARING A POLYMERIC RELIEF STRUCTURE STICHTING DUTCH POLYMER INSTITUTE (NL) 2011-05-05 US disclosed
EP-2260353-A1 PROCESS FOR PREPARING A POLYMERIC RELIEF STRUCTURE Stichting Dutch Polymer Institute (NL) 2010-12-15 EP disclosed
WO-2009124942-A1 PROCESS FOR PREPARING A POLYMERIC RELIEF STRUCTURE STICHTING DUTCH POLYMER INSTITUTE (NL) 2009-10-15 WO disclosed
EP-2109005-A1 Process for preparing a polymeric relief structure Stichting Dutch Polymer Institute (NL) 2009-10-14 EP disclosed