Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 10/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18854938 | 0.90 | NOTUM (0.36) | NOTUM | |
| SCHEMBL18866338 | 0.88 | POLB (0.40) | POLBDDR1SMN1; SMN2HPGDLRRK2 | |
| SCHEMBL18866373 | 0.87 | POLB (0.40) | POLBDDR1 | |
| SCHEMBL18866479 | 0.86 | POLB (0.39) | POLBDDR1 | |
| SCHEMBL18864234 | 0.85 | POLB (0.39) | POLBDDR1 | |
| SCHEMBL18866478 | 0.85 | POLB (0.39) | POLBDDR1 | |
| SCHEMBL18866471 | 0.85 | POLB (0.39) | POLBDDR1 | |
| SCHEMBL18866410 | 0.85 | POLB (0.38) | POLBDDR1 | |
| SCHEMBL18923941 | 0.85 | POLB (0.38) | POLBDDR1 | |
| SCHEMBL31141500 | 0.84 | POLB (0.46) | POLBDDR1LRRK2MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9668482-B1 | Fused heterocyclic compound and pest control application thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-06-06 | — | — | US | disclosed |
| US-20170135348-A1 | FUSED HETEROCYCLIC COMPOUND AND PEST CONTROL APPLICATION THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170135348-A1 | FUSED HETEROCYCLIC COMPOUND AND PEST CONTROL APPLICATION THEREOF | KEAP1, DDT, CYP4B1 | POLB 4756/4885NOTUM 241/4885DDR1 4530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.