Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.45 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10019206 | 0.90 | MAPT (0.49) | HTR2ATAAR1 | |
| SCHEMBL10190393 | 0.86 | TAAR1 (0.56) | HTR2ATAAR1HTR1AHTR2CHTR2B | |
| SCHEMBL28663880 | 0.84 | HTR2A (0.47) | HTR2ATAAR1TRAP1 | |
| SCHEMBL5300541 | 0.84 | HTR2A (0.72) | HTR2ATAAR1HTR1AHTR2CHTR2B | |
| SCHEMBL26782443 | 0.83 | HTR2A (0.50) | HTR2ATAAR1HTR1AHTR2CHTR2B | |
| SCHEMBL14113379 | 0.83 | HTR2A (0.70) | HTR2ATAAR1HTR1AHTR2CHTR2B | |
| SCHEMBL12722553 | 0.81 | HTR2A (0.44) | HTR2A | |
| SCHEMBL26053886 | 0.80 | TAAR1 (0.46) | HTR2ATAAR1HTR1AHTR2CHTR2B | |
| SCHEMBL18867908 | 0.78 | HTR2A (0.48) | HTR2AP2RX3P2RX2TAAR1HTR1A | |
| SCHEMBL21102072 | 0.78 | HTR2A (0.56) | HTR2AP2RX3P2RX2TAAR1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170137341-A1 | FLUORINATION METHOD | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2017-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170137341-A1 | FLUORINATION METHOD | F13B, PPARG, PGC | HTR2A 4287/4885P2RX3 1127/4885P2RX2 1003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.