Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 1/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.42 |
| ▸ | ITGAL | P20701 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GPR183 | P32249 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13894064 | 0.85 | ITGB2 (0.51) | ITGB2ICAM1ITGAL | |
| SCHEMBL18362352 | 0.79 | HDAC6 (0.42) | ITGB2ICAM1ITGALNPC1RAB9A | |
| SCHEMBL18868105 | 0.79 | ITGB2 (0.61) | ITGB2ICAM1ITGAL | |
| SCHEMBL13292407 | 0.79 | ITGB2 (0.57) | ITGB2ICAM1ITGAL | |
| SCHEMBL19158567 | 0.76 | ITGB2 (0.69) | ITGB2ICAM1ITGAL | |
| SCHEMBL4755846 | 0.76 | ITGB2 (0.69) | ITGB2ICAM1ITGAL | |
| SCHEMBL13662090 | 0.76 | ITGB2 (0.56) | ITGB2ICAM1ITGAL | |
| SCHEMBL13813568 | 0.76 | ITGB2 (0.77) | ITGB2ICAM1ITGAL | |
| SCHEMBL23979102 | 0.76 | ITGB2 (0.58) | ITGB2ICAM1ITGALHDAC6 | |
| SCHEMBL12169875 | 0.75 | ITGB2 (0.62) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3167886-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF MACULAR EDEMA | SARcode Bioscience Inc. (US) | 2017-05-17 | — | — | EP | disclosed |