Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.51 |
| ▸ | MEN1 | O00255 | 8/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | INSR | P06213 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 5/20 | 0.42 |
| ▸ | USP2 | O75604 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 3/20 | 0.42 |
| ▸ | CASP7 | P55210 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HBB | P68871 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18868131 | 0.91 | MAPT (0.56) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL18868143 | 0.88 | MAPT (0.53) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL18868148 | 0.88 | MAPT (0.53) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL61593 | 0.88 | MAPT (0.53) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL18868145 | 0.86 | MAPT (0.57) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL18868132 | 0.86 | MAPT (0.51) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL61619 | 0.85 | MAPT (0.49) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL17151380 | 0.84 | MAPT (0.49) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL17151523 | 0.84 | INSR (0.53) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL18868138 | 0.84 | MEN1 (0.51) | MAPTMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170137418-A1 | SMALL MOLECULAR PROBES, PROCESSES AND USE THEREOF | JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) | 2017-05-18 | — | — | US | disclosed |
| US-20170137418-A1 | SMALL MOLECULAR PROBES, PROCESSES AND USE THEREOF | JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) | 2017-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170137418-A1 | SMALL MOLECULAR PROBES, PROCESSES AND USE THEREOF | APBA1, APP, PRNP | MAPT 26/4885MEN1 1123/4885KMT2A 3252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.