Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 19/20 | 0.60 |
| ▸ | ICAM1 | P05362 | 19/20 | 0.60 |
| ▸ | ITGAL | P20701 | 19/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL879313 | 0.85 | ITGB2 (0.66) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL20903203 | 0.85 | ITGB2 (0.66) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL22464799 | 0.85 | ITGB2 (0.49) | ITGB2ICAM1ITGALCYP2C9L3MBTL1 | |
| Hydrochloric Acid SCHEMBL20680587 | 0.85 | ITGB2 (0.65) | ITGB2ICAM1ITGALCYP2C9 | |
| Hydrochloric Acid SCHEMBL20680588 | 0.85 | ITGB2 (0.65) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL19158451 | 0.82 | ITGB2 (0.67) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL15445327 | 0.81 | ITGB2 (0.46) | ITGB2ICAM1ITGALCYP2C9L3MBTL1 | |
| SCHEMBL13588336 | 0.79 | POLB (0.48) | ITGB2ICAM1ITGALCYP2C9 | |
| SCHEMBL19134123 | 0.79 | ITGB2 (0.42) | ITGB2ICAM1ITGALCYP2C9L3MBTL1 | |
| SCHEMBL15445340 | 0.79 | ITGB2 (0.59) | ITGB2ICAM1ITGALCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3167886-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF MACULAR EDEMA | SARcode Bioscience Inc. (US) | 2017-05-17 | — | — | EP | disclosed |