Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1608668 | 0.69 | NAPRT (0.32) | — | |
| SCHEMBL28431729 | 0.67 | ALDH1A1 (0.44) | POLB | |
| SCHEMBL736923 | 0.64 | — | — | |
| SCHEMBL2850012 | 0.64 | DAO (0.37) | POLB | |
| SCHEMBL1059399 | 0.63 | ALDH1A1 (0.41) | — | |
| Hydrochloric Acid SCHEMBL27659745 | 0.63 | DAO (0.38) | POLB | |
| SCHEMBL27534263 | 0.63 | DAO (0.38) | POLB | |
| Benzene SCHEMBL28468895 | 0.63 | TSHR (0.42) | POLB | |
| SCHEMBL22494215 | 0.62 | — | — | |
| SCHEMBL329181 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785659-B2 | Method for the production of sulphonylpyrroles as HDAC inhibitors | 4SC AG (DE) | 2014-07-22 | — | — | US | disclosed |
| EP-2265580-B1 | NOVEL METHOD FOR THE PRODUCTION OF SULPHONYLPYRROLES AS HDAC INHIBITORS | 4SC AG (DE) | 2011-08-10 | — | — | EP | disclosed |
| US-20110105568-A1 | NOVEL METHOD FOR THE PRODUCTION OF SULPHONYLPYRROLES AS HDAC INHIBITORS | 4SC AG (DE) | 2011-05-05 | — | — | US | disclosed |
| EP-2265580-A1 | NOVEL METHOD FOR THE PRODUCTION OF SULPHONYLPYRROLES AS HDAC INHIBITORS | 4SC AG (DE) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009112529-A1 | NOVEL METHOD FOR THE PRODUCTION OF SULPHONYLPYRROLES AS HDAC INHIBITORS | 4SC AG (DE) | 2009-09-17 | — | — | WO | disclosed |
| EP-2100878-A1 | Novel method for the production of sulphonylpyrroles as HDAC inhibitors | 4SC AG (DE) | 2009-09-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105568-A1 | NOVEL METHOD FOR THE PRODUCTION OF SULPHONYLPYRROLES AS HDAC INHIBITORS | HDAC1, HDAC2, HDAC3 | POLB 2543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.