Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | F10 | P00742 | 2/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.48 |
| ▸ | F7 | P08709 | 2/20 | 0.48 |
| ▸ | F3 | P13726 | 2/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27851541 | 0.86 | F2 (0.47) | F2F10PRSS1PRSS2F7 | |
| SCHEMBL10600485 | 0.84 | ACHE (0.58) | F2F10PRSS1PRSS2F7 | |
| SCHEMBL6425698 | 0.84 | ACHE (0.58) | F2F10PRSS1PRSS2F7 | |
| SCHEMBL7281732 | 0.84 | ACHE (0.58) | F2F10PRSS1PRSS2F7 | |
| SCHEMBL18832485 | 0.84 | ACHE (0.58) | F2F10PRSS1PRSS2F7 | |
| SCHEMBL7271123 | 0.83 | F2 (0.48) | KEAP1NFE2L2F2F10PRSS1 | |
| SCHEMBL9360975 | 0.83 | F2 (0.49) | F2F10PRSS1PRSS2F7 | |
| SCHEMBL9360982 | 0.83 | F2 (0.49) | F2F10PRSS1PRSS2F7 | |
| SCHEMBL7271279 | 0.83 | MEN1 (0.45) | F2F10PRSS1PRSS2F7 | |
| SCHEMBL8886562 | 0.83 | HPGD (0.49) | F2F10PRSS1PRSS2F7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017081206-A1 | PROCESSES FOR THE PREPARATION OF DIASTEREOMERICALLY AND ENANTIOMERICALLY ENRICHED OXAZOLINES | Química Sintética, S.A. (ES) | 2017-05-18 | — | — | WO | disclosed |