Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 11/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15628432 | 0.84 | GBA1 (0.40) | GBA1CYP19A1KDM4ETP53 | |
| SCHEMBL19723359 | 0.82 | GBA1 (0.36) | GBA1CYP19A1KDM4ETP53ACHE | |
| SCHEMBL16263165 | 0.79 | GBA1 (0.35) | GBA1CYP19A1KDM4ETP53 | |
| SCHEMBL23417749 | 0.77 | GBA1 (0.62) | GBA1 | |
| SCHEMBL21063549 | 0.77 | CYP4F2 (0.40) | GBA1ALK | |
| SCHEMBL22794211 | 0.75 | CYP19A1 (0.58) | GBA1CYP19A1 | |
| SCHEMBL24406787 | 0.75 | GPR88 (0.35) | GBA1ALK | |
| SCHEMBL13471584 | 0.75 | — | — | |
| SCHEMBL23619333 | 0.74 | CYP19A1 (0.38) | GBA1CYP19A1 | |
| SCHEMBL9915128 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170137468-A1 | MODULATION OF COMPLEMENT ACTIVITY | UCB HOLDINGS, INC. | 2017-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170137468-A1 | MODULATION OF COMPLEMENT ACTIVITY | C5, C3AR1, CFH | GBA1 553/4885CYP19A1 3885/4885KDM4E 3632/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.