Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 11/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1009221 | 1.00 | LSS (0.78) | LSS | |
| SCHEMBL1401906 | 1.00 | LSS (0.78) | LSS | |
| SCHEMBL1142772 | 1.00 | LSS (0.78) | LSS | |
| SCHEMBL29711771 | 0.94 | LSS (0.83) | LSS | |
| SCHEMBL29711785 | 0.94 | LSS (0.83) | LSS | |
| SCHEMBL2833064 | 0.90 | LSS (0.66) | LSS | |
| SCHEMBL4583832 | 0.89 | LSS (0.65) | LSS | |
| SCHEMBL4583833 | 0.89 | LSS (0.65) | LSS | |
| SCHEMBL25205292 | 0.86 | LSS (0.71) | LSS | |
| SCHEMBL10048472 | 0.86 | LSS (0.71) | LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030087430-A1 | Mammalian sterol synthesis as a target for chemotherapy against bacteria | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2003-05-08 | — | — | US | claimed |
| WO-2001077366-A1 | POSITIVE SELECTION METHOD, COMPOUNDS, HOST CELLS AND USES THEREOF | CUBIST PHARMACEUTICALS, INC. (US) | 2001-10-18 | — | — | WO | claimed |
| EP-4702036-A1 | METHOD OF PRODUCING TERPENES | Nicoventures Trading Limited (GB) | 2026-03-04 | — | — | EP | disclosed |
| EP-3493811-B1 | SMALL MOLECULE THERAPEUTIC COMPOUNDS THAT REDUCE THE INCIDENCE OF INTRACEREBRAL HEMORRHAGE AND BRAIN MICROHEMORRHAGES | ZEBRAPEUTICS INC (CA) | 2026-01-28 | — | — | EP | disclosed |
| EP-4608876-A2 | ENDOCYTIC AGENTS | BioVentures, LLC (US) | 2025-09-03 | — | — | EP | disclosed |
| CN-120118922-A | Ganoderma lucidum transcription factor Zn-8 and derivatives thereof, and application and method in ganoderic acid synthesis | 浙江寿仙谷医药股份有限公司 | 2025-06-10 | — | — | CN | disclosed |
| CN-119529044-A | Application of ganoderma lucidum transcription factor C2H2-6 in forward regulation and control of ganoderic acid biosynthesis | 浙江寿仙谷医药股份有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-119504964-A | Glossy ganoderma transcription factor GLHB-1 for regulating and controlling transcriptional activity of glossy ganoderma acid synthetic gene LSS and SQS, and encoding gene and application thereof | 浙江寿仙谷医药股份有限公司 | 2025-02-25 | — | — | CN | disclosed |
| US-20250037787-A1 | CONCENTRATION BOUNDS IN LARGE NETWORKS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2025-01-30 | — | — | US | disclosed |
| CN-119061025-A | Ganoderma lucidum transcription factor C3H-2 and application and method thereof in ganoderic acid synthesis | 浙江寿仙谷医药股份有限公司 | 2024-12-03 | — | — | CN | disclosed |
| WO-2024224082-A1 | METHOD OF PRODUCING TERPENES | Nicoventures Trading Limited (GB) | 2024-10-31 | — | — | WO | disclosed |
| EP-0468457-A1 | Novel substituted piperidines and their use as inhibitors of cholesterol synthesis | MERRELL PHARMACEUTICALS INC. (US) | 1992-01-29 | — | — | EP | disclosed |
| WO-1991014668-A1 | NOVEL CYCLOPROPYL SQUALENE DERIVATIVES AND THEIR USE AS INHIBITORS OF CHOLESTEROL SYNTHESIS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-10-03 | — | — | WO | disclosed |
| US-5051534-A | For treatment of vascular disease | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0420116-A2 | Novel substituted alkyl piperidines and their use as inhibitors of cholesterol synthesis | MERRELL PHARMACEUTICALS INC. (US) | 1991-04-03 | — | — | EP | disclosed |
| EP-0404834-A4 | SQUALENE OXIDE CYCLASE INHIBITORS AND THERAPEUTIC USE THEREOF | — | 1991-01-23 | — | — | EP | disclosed |
| EP-0404834-A1 | SQUALENE OXIDE CYCLASE INHIBITORS AND PHARMACEUTICAL COMPOSITION | SOMATOGENETICS INTERNATIONAL, INC. (US) | 1991-01-02 | — | — | EP | disclosed |
| EP-0392808-A2 | Enzyme luminescence assay | THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1990-10-17 | — | — | EP | disclosed |
| WO-1989008450-A1 | SQUALENE OXIDE CYCLASE INHIBITORS AND THERAPEUTIC USE THEREOF | SOMATOGENETICS INTERNATIONAL, INC. (US) | 1989-09-21 | — | — | WO | disclosed |
| US-4863932-A | Squalene oxide cyclase inhibitors and therapeutic use thereof | SOMATOGENETICS INTERNATIONAL, INC. (US) | 1989-09-05 | — | — | US | disclosed |