Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 11/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1401906 | 1.00 | LSS (0.78) | LSS | |
| SCHEMBL1142772 | 1.00 | LSS (0.78) | LSS | |
| SCHEMBL188732 | 1.00 | LSS (0.78) | LSS | |
| SCHEMBL29711771 | 0.94 | LSS (0.83) | LSS | |
| SCHEMBL29711785 | 0.94 | LSS (0.83) | LSS | |
| SCHEMBL2833064 | 0.90 | LSS (0.66) | LSS | |
| SCHEMBL4583832 | 0.89 | LSS (0.65) | LSS | |
| SCHEMBL4583833 | 0.89 | LSS (0.65) | LSS | |
| SCHEMBL25205292 | 0.86 | LSS (0.71) | LSS | |
| SCHEMBL10048472 | 0.86 | LSS (0.71) | LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260139286-A1 | MICROBIAL PRODUCTION OF TRITERPENOIDS INCLUDING MOGROSIDES | MANUS BIO INC (US) | 2026-05-21 | — | — | US | claimed |
| EP-3877519-B1 | BIOSYNTHESIS OF MOGROSIDES | GINKGO BIOWORKS INC (US) | 2026-03-11 | — | — | EP | claimed |
| US-12570991-B2 | Recombinant yeast strain having sterol productivity, preparation method therefor and use thereof | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2026-03-10 | — | — | US | claimed |
| EP-4698673-A1 | STRAINS AND METHODS FOR THE PRODUCTION OF MOGROSIDES | DSM IP Assets B.V. (NL) | 2026-02-25 | — | — | EP | claimed |
| US-20250346914-A1 | SAPONARIOSIDE BIOSYNTHETIC ENZYMES | PLANT BIOSCIENCE LTD (GB) | 2025-11-13 | — | — | US | claimed |
| EP-3399041-B1 | ENHANCEMENT OF GINSENOSIDE PRODUCTION BY IMPROVEMENT OF YEAST CELL ORGANELLE | KOREA RES INST CHEMICAL TECH (KR) | 2025-10-22 | — | — | EP | claimed |
| US-12404516-B2 | Method to obtain low triterpene/triterpenoid-containing natural rubber latex | FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 2025-09-02 | — | — | US | claimed |
| US-12391963-B2 | Metabolic engineering | PLANT BIOSCIENCE LIMITED (GB) | 2025-08-19 | — | — | US | claimed |
| WO-2025101625-A1 | ENZYMES, HOST CELLS, AND METHODS FOR PRODUCING MOGROSIDES | MANUS BIO INC. (US) | 2025-05-15 | — | — | WO | claimed |
| EP-4547833-A1 | SAPONARIOSIDE BIOSYNTHETIC ENZYMES | Plant Bioscience Limited (GB) | 2025-05-07 | — | — | EP | claimed |
| US-20070016982-A1 | Transgenic plants with increased titerpene saponin levels | E. I. DU PONT DE NEMOURS AND COMPANY | 2007-01-18 | — | — | US | claimed |
| US-20050222071-A1 | Topical administration of at least one double-stranded RNA oligonucleotide (dsRNA) | L'OREAL (FR) | 2005-10-06 | — | — | US | claimed |
| EP-1499177-A4 | TRANSGENIC PLANTS WITH A SUPPRESSED TRITERPENE LEVEL | DU PONT (US) | 2005-09-21 | — | — | EP | claimed |
| EP-1513482-A2 | TOPICAL USE OF AT LEAST ONE DOUBLE-STRANDED RNA OLIGONUCLEOTIDE (DS RNA) | L'OREAL (FR) | 2005-03-16 | — | — | EP | claimed |
| EP-1499177-A2 | TRANSGENIC PLANTS WITH A SUPPRESSED TRITERPENE LEVEL | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2005-01-26 | — | — | EP | claimed |
| US-6747056-B2 | STREPTOMYCES HAS ABILITY TO PRODUCE K99- 5041-C1X, INHIBITORY ACTIVITY AGAINST LANOSTEROL SYNTHASE, PREVENTIVE AND THERAPEUTIC AGENTS CAUSED BY ACCUMULATION OF CHOLESTEROL IN HUMANS AND ANTIFUNGAL AGENTS. | THE KITASATO INSTITUTE (JP) | 2004-06-08 | — | — | US | claimed |
| US-20040010818-A1 | Use of recombinant DNA fragments encoding at least a portion of an oxidosqualene cyclase to lower the level of a triterpene in plants and seeds; method for reducing saponin level in a transgenic soybean plant | MCGONIGLE BRIAN (US) | 2004-01-15 | — | — | US | claimed |
| US-20040002533-A1 | Novel K99-5041 substance and production thereof | THE KITASATO INSTITUTE (JP) | 2004-01-01 | — | — | US | claimed |
| WO-2003101376-A2 | TOPICAL USE OF AT LEAST ONE DOUBLE-STRANDED RNA OLIGONUCLEOTIDE (DS RNA) | L'OREAL (FR) | 2003-12-11 | — | — | WO | claimed |
| WO-2003095615-A2 | TRANSGENIC PLANTS WITH A SUPPRESSED TRITERPENE LEVEL | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-11-20 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040002533-A1 | Novel K99-5041 substance and production thereof | CYP51A1, LSS, CYP46A1 | LSS 2/4885 |
| US-20050222071-A1 | Topical administration of at least one double-stranded RNA oligonucleotide (dsRNA) | DCLRE1B, POLRMT, ADAR | LSS 4041/4885 |
| US-20260139286-A1 | MICROBIAL PRODUCTION OF TRITERPENOIDS INCLUDING MOGROSIDES | POR, GALE, CYP51A1 | LSS 31/4885 |
| US-12570991-B2 | Recombinant yeast strain having sterol productivity, preparation method therefor and use thereof | ERG28, CYP46A1, CYP51A1 | LSS 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.