Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.43 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | EBP | Q15125 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18874338 | 0.92 | LPAR1 (0.47) | LPAR1SIGMAR1C5AR1NPC1RAB9A | |
| SCHEMBL18874043 | 0.89 | LPAR1 (0.48) | LPAR1SIGMAR1C5AR1NPC1RAB9A | |
| SCHEMBL18874186 | 0.88 | LPAR1 (0.49) | LPAR1SIGMAR1C5AR1NPC1RAB9A | |
| SCHEMBL18874318 | 0.88 | LPAR1 (0.46) | LPAR1SIGMAR1C5AR1NPC1RAB9A | |
| SCHEMBL18873914 | 0.88 | POLB (0.48) | LPAR1SIGMAR1POLB | |
| SCHEMBL18874173 | 0.86 | LPAR1 (0.46) | LPAR1SIGMAR1C5AR1NPC1RAB9A | |
| SCHEMBL18873889 | 0.86 | LPAR1 (0.46) | LPAR1SIGMAR1C5AR1NPC1RAB9A | |
| SCHEMBL1560903 | 0.86 | LPAR1 (0.63) | LPAR1SIGMAR1NPC1RAB9APDE4A | |
| SCHEMBL18874305 | 0.83 | LPAR1 (0.51) | LPAR1SIGMAR1C5AR1NPC1RAB9A | |
| SCHEMBL18874390 | 0.81 | LPAR1 (0.51) | LPAR1SIGMAR1NPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303270-B1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-17 | — | — | EP | disclosed |