Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.47 |
| ▸ | PDE4A | P27815 | 3/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18874043 | 0.90 | LPAR1 (0.48) | LPAR1SIGMAR1NPC1RAB9APOLB | |
| SCHEMBL18874338 | 0.89 | LPAR1 (0.47) | LPAR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL18873947 | 0.88 | LPAR1 (0.47) | LPAR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL18874173 | 0.87 | LPAR1 (0.46) | LPAR1SIGMAR1MCHR1NPC1RAB9A | |
| SCHEMBL18873914 | 0.86 | POLB (0.48) | LPAR1SIGMAR1POLB | |
| SCHEMBL18874318 | 0.86 | LPAR1 (0.46) | LPAR1SIGMAR1NPC1RAB9APOLB | |
| SCHEMBL18873889 | 0.86 | LPAR1 (0.46) | LPAR1SIGMAR1NPC1RAB9APOLB | |
| SCHEMBL1561364 | 0.86 | LPAR1 (0.65) | LPAR1MRGPRX4PDE4APDE4BPDE4C | |
| SCHEMBL18874390 | 0.82 | LPAR1 (0.51) | LPAR1SIGMAR1NPC1RAB9APOLB | |
| SCHEMBL18874305 | 0.82 | LPAR1 (0.51) | LPAR1SIGMAR1NPC1RAB9AC5AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303270-B1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-17 | — | — | EP | disclosed |