Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | EBP | Q15125 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1561205 | 0.87 | LPAR1 (0.61) | LPAR1ALOX5ACHEHDAC1HDAC2 | |
| SCHEMBL18874390 | 0.86 | LPAR1 (0.51) | LPAR1ALOX5SIRT2SIGMAR1ACHE | |
| SCHEMBL18874305 | 0.82 | LPAR1 (0.51) | LPAR1ALOX5SIRT2SIGMAR1HDAC1 | |
| SCHEMBL18873929 | 0.79 | LPAR1 (0.55) | LPAR1ALOX5SIRT2SIGMAR1HDAC1 | |
| SCHEMBL18873931 | 0.79 | LPAR1 (0.53) | LPAR1ALOX5SIRT2SIGMAR1HDAC1 | |
| SCHEMBL18874049 | 0.79 | LPAR1 (0.55) | LPAR1ALOX5SIRT2SIGMAR1 | |
| SCHEMBL1560794 | 0.79 | LPAR1 (0.71) | LPAR1SIGMAR1ACHEHDAC1HDAC2 | |
| SCHEMBL26242451 | 0.79 | LPAR1 (0.64) | LPAR1SIGMAR1ACHEHDAC1MAPT | |
| SCHEMBL18874414 | 0.78 | LPAR1 (0.51) | LPAR1ALOX5SIRT2SIGMAR1HDAC1 | |
| SCHEMBL18874036 | 0.78 | LPAR1 (0.56) | LPAR1SIRT2SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303270-B1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-17 | — | — | EP | disclosed |