Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.56 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.43 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.37 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18873882 | 0.93 | LPAR1 (0.56) | LPAR1CXCR5C5AR1SIRT2 | |
| SCHEMBL18874205 | 0.92 | LPAR1 (0.56) | LPAR1C5AR1SIRT2 | |
| SCHEMBL18874159 | 0.90 | LPAR1 (0.57) | LPAR1CXCR5C5AR1SIRT2POLB | |
| SCHEMBL18874171 | 0.89 | LPAR1 (0.55) | LPAR1CXCR5C5AR1SIRT2KMT2A | |
| SCHEMBL18874189 | 0.89 | LPAR1 (0.58) | LPAR1CXCR5C5AR1SIRT2KMT2A | |
| SCHEMBL18874199 | 0.88 | LPAR1 (0.57) | LPAR1CXCR5C5AR1SIRT2POLB | |
| SCHEMBL18873905 | 0.88 | LPAR1 (0.57) | LPAR1CXCR5C5AR1SIRT2POLB | |
| SCHEMBL18873861 | 0.86 | LPAR1 (0.75) | LPAR1CXCR5C5AR1SIRT2POLB | |
| SCHEMBL18873898 | 0.86 | LPAR1 (0.56) | LPAR1CXCR5SIRT2KMT2AMEN1 | |
| SCHEMBL18874045 | 0.86 | LPAR1 (0.56) | LPAR1CXCR5SIRT2KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303270-B1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-17 | — | — | EP | disclosed |