Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 14/20 | 0.46 |
| ▸ | LATS2 | Q9NRM7 | 10/20 | 0.46 |
| ▸ | GPR6 | P46095 | 4/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14621191 | 0.86 | LATS1 (0.46) | LATS1LATS2GPR6 | |
| SCHEMBL4867888 | 0.84 | GLP1R (0.34) | GPR6JAK2 | |
| SCHEMBL1882014 | 0.81 | LATS1 (0.41) | LATS1LATS2GPR6JAK2 | |
| SCHEMBL1892023 | 0.79 | F7 (0.38) | LATS1LATS2JAK2 | |
| SCHEMBL4866761 | 0.79 | MAPK14 (0.34) | — | |
| SCHEMBL1882670 | 0.76 | MAPK14 (0.39) | JAK2 | |
| SCHEMBL4863732 | 0.76 | GPR6 (0.34) | GPR6 | |
| SCHEMBL12660311 | 0.73 | MAPK14 (0.35) | — | |
| SCHEMBL4870273 | 0.72 | PRKD3 (0.33) | JAK2 | |
| SCHEMBL4155726 | 0.67 | MAPK14 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7947679-B2 | Fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-05-24 | — | — | US | disclosed |
| US-7947679-B2 | Fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-05-24 | — | — | US | disclosed |
| US-7947679-B2 | Fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-05-24 | — | — | US | disclosed |
| EP-1585746-B1 | NAPHTHYRIDINE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA LTD (GB) | 2007-01-31 | — | — | EP | disclosed |
| EP-1585746-B1 | NAPHTHYRIDINE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA LTD (GB) | 2007-01-31 | — | — | EP | disclosed |
| US-20060069089-A1 | Fungicides | SYNGENTA CROP PROTECTION, INC. | 2006-03-30 | — | — | US | disclosed |
| EP-1585746-A2 | NAPHTHYRIDINE DERIVATIVES AND THEIR USE AS FUNGICIDES | Syngenta Limited (GB) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004056824-A2 | NAPHTHYRIDINE DERIVATIVES AND THEIR USE AS FUNGICIDES | SYNGENTA LIMITED (GB) | 2004-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060069089-A1 | Fungicides | CBR3, TACR3, HCRTR1 | LATS1 3619/4885LATS2 3593/4885GPR6 390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.