SCHEMBL4863732

SCHEMBL4863732

CC(C)Nc1nc2ccnnc2c(Cl)c1-c1c(F)cc(F)cc1F

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GPR6 P46095 2/20 0.34
PIM1 P11309 1/20 0.33
PIM2 Q9P1W9 1/20 0.33
MAP4K4 O95819 1/20 0.32
GLP1R P43220 1/20 0.32
MAPK14 Q16539 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14086466 0.89 GLP1R (0.37) GLP1RMAPK14
SCHEMBL4149816 0.82 MAPK14 (0.32) PIM1PIM2MAPK14
SCHEMBL4866761 0.81 MAPK14 (0.34) MAPK14
SCHEMBL4162294 0.79
SCHEMBL4867888 0.77 GLP1R (0.34) GPR6GLP1RMAPK14
SCHEMBL4870273 0.77 PRKD3 (0.33) MAP4K4MAPK14
SCHEMBL1887545 0.76 LATS1 (0.46) GPR6
SCHEMBL5224807 0.76 MAP4K4 (0.32) MAP4K4
SCHEMBL13906899 0.73 MAPK14 (0.33) GLP1RMAPK14
SCHEMBL1882670 0.71 MAPK14 (0.39) MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7410967-B2 Pyridodiazines as plant fungicides SYNGENTA CROP PROTECTION, INC. (US) 2008-08-12 US disclosed
US-7410967-B2 Pyridodiazines as plant fungicides SYNGENTA CROP PROTECTION, INC. (US) 2008-08-12 US disclosed
US-7410967-B2 Pyridodiazines as plant fungicides SYNGENTA CROP PROTECTION, INC. (US) 2008-08-12 US disclosed
US-20060205717-A1 Pyridodiazines as plant fungicides SYNGENTA CROP PROTECTION, INC. 2006-09-14 US disclosed
EP-1575948-A1 PYRIDODIAZINES AS PLANT FUNGICIDES Syngenta Limited (GB) 2005-09-21 EP disclosed
WO-2004056825-A1 PYRIDODIAZINES AS PLANT FUNGICIDES SYNGENTA LIMITED (GB) 2004-07-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060205717-A1 Pyridodiazines as plant fungicides CYP4Z1, CYP4X1, PNPO GPR6 3441/4885PIM1 2488/4885PIM2 2634/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.