Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13508606 | 1.00 | POLB (0.39) | POLBSPHK1LMNACYP2C19HSD17B10 | |
| SCHEMBL18875659 | 1.00 | POLB (0.39) | POLBSPHK1LMNACYP2C19HSD17B10 | |
| SCHEMBL18875598 | 1.00 | POLB (0.39) | POLBSPHK1LMNACYP2C19HSD17B10 | |
| SCHEMBL14505233 | 1.00 | POLB (0.39) | POLBSPHK1LMNACYP2C19HSD17B10 | |
| SCHEMBL14505238 | 1.00 | POLB (0.39) | POLBSPHK1LMNACYP2C19HSD17B10 | |
| SCHEMBL18875597 | 1.00 | POLB (0.39) | POLBSPHK1LMNACYP2C19HSD17B10 | |
| SCHEMBL18875721 | 1.00 | POLB (0.39) | POLBSPHK1LMNACYP2C19HSD17B10 | |
| SCHEMBL18875595 | 1.00 | POLB (0.39) | POLBSPHK1LMNACYP2C19HSD17B10 | |
| SCHEMBL18875706 | 1.00 | POLB (0.39) | POLBSPHK1LMNACYP2C19HSD17B10 | |
| SCHEMBL18875585 | 1.00 | POLB (0.39) | POLBSPHK1LMNACYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170146549-A1 | ISOBARIC MASS LABELS | ELECTROPHORETICS LIMITED (GB) | 2017-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170146549-A1 | ISOBARIC MASS LABELS | SRMS, PTMS, QPCTL | POLB 2893/4885SPHK1 4834/4885LMNA 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.